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Comment
. 2025 Jun 12;388(6752):1132-1133.
doi: 10.1126/science.ady7161. Epub 2025 Jun 12.

Rethinking jaundice

Joachim Kloehn  1 , Dominique Soldati-Favre  1
Affiliations
Comment

Rethinking jaundice

Joachim Kloehn et al. Science. .

Abstract

A buildup of unconjugated bilirubin may be a protective response to malaria.

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  • A metabolite-based resistance mechanism against malaria.
    Figueiredo A, Rastogi ST, Ramos S, Nogueira F, De Villiers K, de Sousa AGG, Votborg-Novél L, von Wedel C, Tober-Lau P, Jentho E, Pagnotta S, Mesquita M, Cardoso S, Bortolussi G, Muro AF, Tranfield EM, Thibaud J, Duarte D, Sousa AL, Pinto SN, Kitoko J, Mombo-Ngoma G, Mischlinger J, Junttila S, Alenquer M, Amorim MJ, Vasavda C, Bosma PJ, Violante S, Drotleff B, Paixão T, Portugal S, Kurth F, Elo LL, Paul BD, Martins R, Soares MP. Figueiredo A, et al. Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12. Science. 2025. PMID: 40504905

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