Human milk as a microbial pacemaker

Liat Shenhav¹, Meghan B Azad², Michael A Silverman³

Affiliations

¹ Institute for systems genetics, New York Grossman School of Medicine, New York University, New York, NY, USA; Department of Microbiology, New York Grossman School of Medicine, New York University, New York, NY, USA; Department of Obstetrics and Gynecology, New York Grossman School of Medicine, New York University, New York, NY, USA; Department of Computer Science, New York University, New York, NY, USA. Electronic address: liat.shenhav@nyulangone.org.
² Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada; Manitoba Interdisciplinary Lactation Centre (MILC), Children's Hospital Research Institute of Manitoba, Winnipeg, MB, Canada.
³ Division of Infectious Disease, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

PMID: 40505616
DOI: 10.1016/j.chom.2025.05.018

Human milk as a microbial pacemaker

Liat Shenhav et al. Cell Host Microbe. 2025.

. 2025 Jun 11;33(6):762-765.

doi: 10.1016/j.chom.2025.05.018.

Authors

Liat Shenhav¹, Meghan B Azad², Michael A Silverman³

Affiliations

¹ Institute for systems genetics, New York Grossman School of Medicine, New York University, New York, NY, USA; Department of Microbiology, New York Grossman School of Medicine, New York University, New York, NY, USA; Department of Obstetrics and Gynecology, New York Grossman School of Medicine, New York University, New York, NY, USA; Department of Computer Science, New York University, New York, NY, USA. Electronic address: liat.shenhav@nyulangone.org.
² Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada; Manitoba Interdisciplinary Lactation Centre (MILC), Children's Hospital Research Institute of Manitoba, Winnipeg, MB, Canada.
³ Division of Infectious Disease, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

PMID: 40505616
DOI: 10.1016/j.chom.2025.05.018

Abstract

A Nature Medicine paper by Sawhney et al.¹ presents a strain-resolved analysis of the gut microbiome from infancy through eight years of age, identifying weaning as an evolutionary trigger for microbial adaptation. Their findings refine the timeline of microbiome development and highlight human milk as a pacemaker of microbial succession.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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Human milk as a microbial pacemaker

Affiliations

Human milk as a microbial pacemaker

Authors

Affiliations

Abstract

Conflict of interest statement

MeSH terms

LinkOut - more resources

Full Text Sources