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. 2025 May;17(Suppl 1):S608-S610.
doi: 10.4103/jpbs.jpbs_531_25. Epub 2025 May 10.

Comparative Analysis of Physicocomechanical Properties of MTA and Biodentine with Addition of Graphene Oxide to MTA and Biodentine: An In-vitro Study

Tanvi Arvind Jagtap  1 , Budhabhushan A Sonvane  2 , Guruprasad Handal  3 , Jayashri Nimba Bhangare  4 , Kedar Vilas Saraf  5 , Abhishek Mulay  6
Affiliations

Comparative Analysis of Physicocomechanical Properties of MTA and Biodentine with Addition of Graphene Oxide to MTA and Biodentine: An In-vitro Study

Tanvi Arvind Jagtap et al. J Pharm Bioallied Sci. 2025 May.

Abstract

Introduction: Bioactive calcium silicate cements (CSCs), such as Mineral Trioxide Aggregate (MTA) and Biodentine, are widely used in endodontic procedures to repair and regenerate tooth pulp and hard tissues. They are valued for being biocompatible, sealing well, and promoting tissue growth. However, they have limitations, like long setting times and weaker bond strength. Graphene oxide, a 2D carbon nanomaterial with exceptional physical and chemical properties, has shown potential in biomedical applications.

Aims and objectives: This study aimed to evaluate the effect of adding 1% graphene oxide to MTA and Biodentine on their setting time and push-out bond strength. This study tested whether adding 1% graphene oxide to MTA and Biodentine could improve their properties.

Materials and methods: 40 samples were divided into four groups: regular MTA, MTA with graphene oxide (MTAG), regular Biodentine (BD), and Biodentine with graphene oxide (BDG). Setting time, push out bond strength were measured.

Results: Results showed that MTAG and BDG set faster and had stronger push out bonds than regular MTA and BD.

Conclusion: These findings suggest graphene oxide could enhance CSCs, making them more effective for dental procedures like pulp capping and perforation repair.

Keywords: Biodentine; MTA; calcium silicate cements; endodontics; graphene oxide; push out bond strength; setting time.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Intra group multiple comparison using Tukey test
Figure 2
Figure 2
Mean push-out bond strength among all four groups
Figure 3
Figure 3
Comparison of all four groups for setting time
Figure 4
Figure 4
Comparison of push-out bond strength among four groups
See this image and copyright information in PMC

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