Review of Osteoporotic Fractures: Occurrence, Prevention, and Consequences
- PMID: 40520052
- PMCID: PMC12167006
- DOI: 10.1055/s-0044-1789220
Review of Osteoporotic Fractures: Occurrence, Prevention, and Consequences
Abstract
Osteoporosis is a metabolic condition that compromises bone density and architecture, increasing the risk of fractures and impacting morbidity and mortality. The diagnosis involves bone densitometry, in which mineral density in areas prone to fractures is assessed. Primary osteoporosis is age-related and may remain asymptomatic for years, while secondary osteoporosis results from comorbidities or medications. Approximately 80% of postmenopausal Caucasian women have osteoporosis, with an expected increase with aging. Orthopedic treatments are common for fractures, which are often caused by falls in the elderly. Fracture prevention requires public health policies and therapies focused on this goal.
A osteoporose é uma condição metabólica que compromete a densidade e a arquitetura ósseas, o que aumenta o risco de fraturas e tem impacto na morbimortalidade. O diagnóstico envolve a densitometria óssea, em que se avalia a densidade mineral em áreas propensas a fraturas. A osteoporose primária, relacionada à idade, pode permanecer assintomática por anos, ao passo que a secundária resulta de comorbidades ou medicamentos. Cerca de 80% das mulheres brancas na pós-menopausa têm osteoporose, com expectativa de aumento com o envelhecimento. Tratamentos ortopédicos são comuns para fraturas, que são frequentemente causadas por quedas em idosos. A prevenção de fraturas é crucial, e requer políticas de saúde pública e terapias com este objetivo.
Keywords: diagnosis; fractures, stress; osteoporosis; risk assessment; treatment.
The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit ( https://creativecommons.org/licenses/by/4.0/ ).
Conflict of interest statement
Conflict of Interests The authors have no conflict of interests to delcare.
Figures
References
-
- on behalf of the World Health Organization Scientific Group (WHO) Kanis J A.Assessment of osteoporosis at the primary health-care level. Technical Report World Health Organization Collaborating Centre for Metabolic Bone Diseases, University of Sheffield, UK; 2007. Available from:https://www.iofbonehealth.org/sites/default/files/WHO_Technical_Report-2...
-
- World Health Organization (WHO) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: report of a WHO study group [meeting held in Rome from 22 to 25 June 1992]; 1994Available from:https://apps.who.int/iris/handle/10665/39142 - PubMed
-
- Gullberg B, Johnell O, Kanis J A. World-wide projections for hip fracture. Osteoporos Int. 1997;7(05):407–413. - PubMed
-
- Liu J, Guo H, Rai P, Pinto L, Barron R. Medication persistence and risk of fracture among female Medicare beneficiaries diagnosed with osteoporosis. Osteoporos Int. 2018;29(11):2409–2417. - PubMed
-
- De Laet C, Odén A, Johansson H, Johnell O, Jönsson B, Kanis J A. The impact of the use of multiple risk indicators for fracture on case-finding strategies: a mathematical approach. Osteoporos Int. 2005;16(03):313–318. - PubMed
LinkOut - more resources
Full Text Sources
