Humanized mice to model rare human diseases

Affiliations

¹ Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843.

Comment

Larry J Suva. Proc Natl Acad Sci U S A. 2025.

. 2025 Jun 24;122(25):e2512731122.

doi: 10.1073/pnas.2512731122. Epub 2025 Jun 16.

¹ Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843.

No abstract available

Conflict of interest statement

Competing interests statement:The author declares no competing interest.

A mouse model of Jansen's metaphyseal chondrodysplasia for investigating disease mechanisms and candidate therapeutics.
Höppner J, Firat D, Parvez-Khan M, Reyes M, Hanna P, Yadav PS, Dean T, Ramos-Torres KM, Brugarolas P, Collins MT, Wein MN, Liu S, Gellman SH, Schipani E, Kronenberg HM, Gardella TJ, Jüppner H. Höppner J, et al. Proc Natl Acad Sci U S A. 2025 Jun 10;122(23):e2500176122. doi: 10.1073/pnas.2500176122. Epub 2025 Jun 2. Proc Natl Acad Sci U S A. 2025. PMID: 40455993

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