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Review
. 2025 Jun 1;43(3):436-441.
doi: 10.7518/hxkq.2025.2024324.

[Hydrogen peroxide and compound chlorhexidine gargle induced anaphylactic shock: a case report and literature review]

[Article in Chinese]
Siyu Zhong  1 , Zhujun Yu  1 , Beibei Ma  1 , Dandan Li  1 , Jianli Wang  1
Affiliations
Review

[Hydrogen peroxide and compound chlorhexidine gargle induced anaphylactic shock: a case report and literature review]

[Article in Chinese]
Siyu Zhong et al. Hua Xi Kou Qiang Yi Xue Za Zhi. .

Abstract
in English, Chinese

Severe allergic reactions to hydrogen peroxide solution and compound chlorhexidine gargle are rare, and most medical professionals have limited understanding of such cases. This article reports a case of anaphylactic shock in a patient with a periodontal abscess following oral flushing with hydrogen peroxide and compound chlorhexidine gargle. Drawing on domestic and international literature, it provides a reference for the emergency management of serious adverse reactions caused by these agents.

过氧化氢溶液和复方氯己定含漱液致严重过敏反应非常少见，大部分医务工作者对其认识不足。本文报道了1例牙周脓肿患者治疗过程中使用过氧化氢和复方氯已定冲洗口腔过程中发生过敏性休克案例，并结合国内外相关文献，以期为过氧化氢和复方氯己定导致的严重不良反应的紧急处置提供参考。.

Keywords: adverse drug reaction; anaphylaxis; compound chlorhexidine gargle; hydrogen peroxide solution.

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Conflict of interest statement

作者声明本文无利益冲突。

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References

    1. 王吉善, 陈晓红, 王圣友, 等. 中国医疗不良事件报告与质量改进的分析研究[J]. 中国卫生质量管理, 2020, 27(6): 28-32.
    2. Wang JS, Chen XH, Wang SY, et al. Analysis and research on reporting and quality improvement of medical adverse events in China[J]. Chin Health Qual Manage, 2020, 27(6): 28-32.
    1. 高雨松, 彭承悦, 宋晓婷, 等. 2017—2023年北京市某医院过敏性休克患者的临床特征分析[J]. 中华预防医学杂志, 2024, 58(4): 474-480.
    2. Gao YS, Peng CY, Song XT, et al. Analysis of the clinical characteristics of patients with anaphylactic shock in a hospital in Beijing city from 2017 to 2023[J]. Chin J Prev Med, 2024, 58(4): 474-480.
    1. 吴先荣. 过氧化氢致不良反应41例临床分析[J]. 广西医学, 2007, 29(4): 549-550.
    2. Wu XR. Clinical analysis of 41 cases of adverse reactions caused by hydrogen peroxide[J]. Guangxi Med J, 2007, 29(4): 549-550.
    1. Sun HL, Chen SZ, Yang C, et al. Advances in the use of chlorhexidine for periodontitis treatment in diabetic patients: a review[J]. Medicine(Baltimore), 2024, 103(36): e39627. - PMC - PubMed
    1. Brookes ZLS, Bescos R, Belfield LA, et al. Current uses of chlorhexidine for management of oral disease: a narrative review[J]. J Dent, 2020, 103: 103497. - PMC - PubMed

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