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. 2025 Oct;22(10):669-671.
doi: 10.1038/s41575-025-01085-5.

The IDEAL framework for machine perfusion in liver transplantation

Otto B van Leeuwen  1 , David Nasralla  2 , Carlo D L Ceresa  2 , Philipp Dutkowski  3 , Peter J Friend  4 , Gabriel C Oniscu  5 , Robert J Porte  6 , Vincent E de Meijer  7 ; COPE 2 Consortium
Collaborators, Affiliations

The IDEAL framework for machine perfusion in liver transplantation

Otto B van Leeuwen et al. Nat Rev Gastroenterol Hepatol. 2025 Oct.
No abstract available

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Conflict of interest statement

Competing interests: D.N. and C.D.L.C. have received consultancy income from OrganOx for assisting with the design and conduct of previous trials. P.J.F. is a co-founder and shareholder in OrganOx and received consultancy payments as non-executive chief medical officer of the company. R.J.P. has received speaker’s honoraria and travel support paid to the institution by XVIVO and Aferetica. V.E.d.M. has received speaker’s honoraria paid to the institution by Astellas, Chiesi and XVIVO. O.B.v.L., P.D. and G.C.O. declare no competing interests.

References

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    1. Schlegel, A. et al. Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation. eBioMedicine 60, 103014 (2020). - DOI - PubMed - PMC
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