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. 2025 Jun;22(6):e70689.
doi: 10.1111/iwj.70689.

Our Experience With Four or More Crystallised Phenol Applications in Pilonidal Sinus Disease

Metin Yalçın  1 , Ahmet Cem Esmer  2
Affiliations

Our Experience With Four or More Crystallised Phenol Applications in Pilonidal Sinus Disease

Metin Yalçın et al. Int Wound J. 2025 Jun.

Abstract

The aim of this study was to analyse the clinical outcomes of patients with pilonidal sinus who underwent daily phenol treatment in the local intervention room of the outpatient clinic. We retrospectively evaluated 53 patients (43 male, 10 female) aged ≥ 18 years who received 4-9 crystallised phenol applications for pilonidal sinus disease. The mean number of phenol applications was 4.84 sessions (range: 4-9). Treatment success was achieved in 92.45% of patients, with a 3-year follow-up. Recurrence occurred in one patient (1.9%), while three patients (5.7%) required surgery due to treatment failure. Complications included skin necrosis (n = 2) and transient pain (n = 2). Phenol treatment is an effective and simple procedure compared to surgical methods, which can be easily applied in outpatient treatment. Therefore, we believe that it can be applied in many sessions to suitable patients without the need for aggressive surgical excision.

Keywords: crystallised phenol; pilonidal sinus; recurrence; repeated application; surgery.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Application of crystallised phenol.
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References

    1. Dogru O., Kargin S., Turan E., Saygin Kerimoğlu R., Nazik E. E., and Ates D., “Long‐Term Outcomes of Crystallized Phenol Application for the Treatment of Pilonidal Sinus Disease,” Journal of Dermatological Treatment 33, no. 3 (2022): 1383–1390, 10.1080/09546634.2020.1818676. - DOI - PubMed
    1. Kayaalp C. and Aydin C., “Review of Phenol Treatment in Sacrococcygeal Pilonidal Disease,” Techniques in Coloproctology 13 (2009): 189–193. - PubMed
    1. Erdogan Mütevelli S., Topal U., Dal F., Akyüz M., and Talih T., “Application of Crystal‐Line Phenol in Pilonidal Sinus Disease A Single‐Center and Single‐Surgeon Experience,” Annali Italiani di Chirurgia 91, no. 5 (2020): 520–525. - PubMed
    1. Foti N., Passannanti D., Libia A., and Campanile F. C., “A Minimally Invasive Approach to Pilonidal Disease With Endoscopic Pilonidal Sinus Treatment(EPSiT): A Single‐Center Case Series With Long‐Term Results,” Techniques in Coloproctology 25 (2021): 1045–1054. - PubMed
    1. Kalaiselvan R., Bathla S., Allen W., Liyanage A., and Rajaganeshan R., “Minimally Invasive Techniques in the Management of Pilonidal Disease,” International Journal of Colorectal Disease 34 (2019): 561–568. - PubMed

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