Setting the record straight: revisiting the debate on extracorporeal therapies in sepsis

Klaus Stahl¹, Pedro David Wendel Garcia^{2

3}, Christian Bode⁴, Sascha David^{5

6}

Affiliations

¹ Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
² Division of Cardiothoracic and Vascular Anaesthesia and Intensive Care Medicine, Department of Anaesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Vienna, Austria.
³ Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
⁴ Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.
⁵ Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. Sascha.david@usz.ch.
⁶ Department of Nephrology, Hannover Medical School, Hannover, Germany. Sascha.david@usz.ch.

PMID: 40524247
PMCID: PMC12168271
DOI: 10.1186/s13054-025-05426-3

Setting the record straight: revisiting the debate on extracorporeal therapies in sepsis

Klaus Stahl et al. Crit Care. 2025.

. 2025 Jun 16;29(1):243.

doi: 10.1186/s13054-025-05426-3.

Authors

Klaus Stahl¹, Pedro David Wendel Garcia^{2

3}, Christian Bode⁴, Sascha David^{5

6}

Affiliations

¹ Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
² Division of Cardiothoracic and Vascular Anaesthesia and Intensive Care Medicine, Department of Anaesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Vienna, Austria.
³ Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
⁴ Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.
⁵ Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. Sascha.david@usz.ch.
⁶ Department of Nephrology, Hannover Medical School, Hannover, Germany. Sascha.david@usz.ch.

PMID: 40524247
PMCID: PMC12168271
DOI: 10.1186/s13054-025-05426-3

No abstract available

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: On behalf of all authors, the corresponding author states that there is no conflict of interest.

References

1. Bottari G, Ranieri VM, Ince C, Pesenti A, Aucella F, Scandroglio AM, et al. Rethinking caution: a critical appraisal of extracorporeal blood purification in sepsis. Crit Care. 2025;29(1):123. - PMC - PubMed
1. Stahl K, Wendel-Garcia PD, Bode C, David S. A few words of caution on blood purification in sepsis. Crit Care. 2025;29(1):45. - PMC - PubMed
1. Wendel Garcia PD, Hilty MP, Held U, Kleinert EM, Maggiorini M. Cytokine adsorption in severe, refractory septic shock. Intensive Care Med. 2021;47(11):1334–6. - PMC - PubMed
1. David S, Bode C, Putensen C, Welte T, Stahl K. Adjuvant therapeutic plasma exchange in septic shock. Intensive Care Med. 2021;47(3):352–4. - PMC - PubMed
1. Kuklin V, Sovershaev M, Bjerner J, Keith P, Scott LK, Thomas OMT, et al. Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis. Crit Care. 2024;28(1):12. - PMC - PubMed

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Setting the record straight: revisiting the debate on extracorporeal therapies in sepsis

Affiliations

Setting the record straight: revisiting the debate on extracorporeal therapies in sepsis

Authors

Affiliations

Conflict of interest statement

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