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. 2025 May 24:15:100182.
doi: 10.1016/j.obpill.2025.100182. eCollection 2025 Sep.

Comorbidities of childhood obesity at a tertiary hospital in Kwazulu-Natal, South Africa

Nasheeta Peer  1   2 , Janice Sewlall  3 , Yusentha Balakrishna  4 , Shafeeka Tayob  5 , Andre-Pascal Kengne  1   2   6 , Yasmeen Ganie  5
Affiliations

Comorbidities of childhood obesity at a tertiary hospital in Kwazulu-Natal, South Africa

Nasheeta Peer et al. Obes Pillars. .

Abstract

Aim: To describe the distribution of childhood obesity and their related comorbidities in <12-year-old children assessed at a South African tertiary hospital from 2012 to 2022.

Methods: In this retrospective electronic chart review, data extracted comprised socio-demographic and lifestyle histories, physical examination and biochemical analyses. World Health Organisation child growth reference defined obesity as z-score ≥2 standard deviations (SD) for 5-19-year-olds, and z-score ≥3 SD for <5-year-olds. Systolic blood pressure and/or diastolic blood pressure ≥95th percentile and 90-94th percentile for age, gender and height, defined hypertension and prehypertension, respectively. Type 2 diabetes and prediabetes diagnoses were based on oral glucose tolerance tests or random blood glucose levels. Dyslipidaemia was deemed present with any abnormality of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides.

Results: Among 430 participants, 52.1 % (n = 224) male, 27.9 % (n = 120) ≤5-years-old and 64.7 % black African, unhealthy lifestyle behaviours were prevalent: 42.3 % spent <30 min/day on physical activity, 43.5 % spent >2 h/day on screen time and 47.9 % consumed soft drinks daily. Family history of obesity (41.9 %), diabetes (40.5 %) and hypertension (40.0 %) was common. Among participants, hypertension (46.1 %) and prehypertension (12.8 %) were high. Type 2 diabetes was low at 1.6 % but prediabetes was 3.3 %. Any dyslipidaemia was prevalent at 30.2 %.

Conclusions: The high burden of cardiometabolic comorbidities in children with obesity warrants concerted interventions at young ages to prevent worsening of comorbidities and the reversal of prehypertension and prediabetes. Unhealthy dietary habits, low activity levels and sedentary behaviours in children need to be urgently targeted to reduce obesity and its comorbidities.

Keywords: Childhood obesity; Dyslipidaemia; Hypertension; Lifestyle; Type 2 diabetes.

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Conflict of interest statement

None of the authors have any competing interests to declare.

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