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Review
. 2025 Jul;46(7):505-507.
doi: 10.1016/j.it.2025.05.005. Epub 2025 Jun 16.

The T cell subsetting challenge

Natalia R Comet  1 , Carmen Gerlach  2
Affiliations
Review

The T cell subsetting challenge

Natalia R Comet et al. Trends Immunol. 2025 Jul.

Abstract

Exploiting specific T cell subset properties bears potential for T cell therapies but is complicated by inconsistencies in T cell subset definitions and markers. Here, we discuss causes for the definition and classification complexities to provide a handle for how to navigate the T cell subset jungle.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.