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. 2025 Jun 17;18(1):103.
doi: 10.1186/s12245-025-00906-3.

Incidence of and risk factors for mortality in children with mushroom poisoning

Jie Cheng  1 , Ya Liu  2 , Shaojun Li  1 , Kaibin Pu  1 , Junming Huo  3 , Liping Tan  4
Affiliations

Incidence of and risk factors for mortality in children with mushroom poisoning

Jie Cheng et al. Int J Emerg Med. .

Abstract

Objective: We aimed to evaluate the incidence of and risk factors for mortality in children with mushroom poisoning.

Methods: Sixty-seven children with mushroom poisoning who were hospitalized at the Children's Hospital of Chongqing Medical University were retrospectively enrolled. The clinical characteristics of the children in the surviving and non-surviving groups were compared. Variables with a P value < 0.1 in the univariate logistic regression analysis were included in the multivariate logistic regression analysis. A receiver operating characteristic (ROC) curve was generated to determine the optimal cutoff point.

Results: The mortality rate of children with mushroom poisoning was 23.88% (16/67), and the incidence of death during hospitalization was 35.02 per 1,000 person-days. The median pediatric sequential organ failure assessment (pSOFA) score was 1.00 (interquartile range [IQR] 0.00-3.00). Logistic regression analysis revealed that the pSOFA score was independently associated with mortality (odds ratio [OR] 4.92, 95% confidence interval [CI] 1.59-62.21; P = 0.040). The optimal cutoff point of the pSOFA score for predicting mortality was 2.00, with an area under the curve (AUC) of 0.84 (95% CI 0.71-0.88, P < 0.001*).

Conclusions: In this study, the incidence of death among children with mushroom poisoning was retrospectively evaluated. The pSOFA score may serve as a good prognostic indicator in children with mushroom poisoning, and children with a pSOFA score ≥ 2 have a significantly increased risk of mortality.

Keywords: Children; Incidence; Mortality; Mushroom poisoning; Risk factors.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: This prospective study was approved by the Ethics Committee of Children’s Hospital of Chongqing Medical University, with approval number (2023 − 538). Informed consent was waived by the Ethics Committee of Children’s Hospital of Chongqing Medical University. No human or animal experiments were involved in this study. All methods were carried out in accordance with the relevant guidelines and regulations. Consent for publication: N/A. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flow chart of the population
Fig. 2
Fig. 2
Number of children with mushroom poisoning in different years
See this image and copyright information in PMC

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