Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 May 16;16(6):935-936.
doi: 10.1021/acsmedchemlett.5c00267. eCollection 2025 Jun 12.

Novel Aryl Hydrocarbon Receptor Agonist Compounds for Treating Psoriasis and Atopic Dermatitis

Ram W Sabnis  1
Affiliations
Editorial

Novel Aryl Hydrocarbon Receptor Agonist Compounds for Treating Psoriasis and Atopic Dermatitis

Ram W Sabnis. ACS Med Chem Lett. .

Abstract

Provided herein are novel aryl hydrocarbon receptor (AHR) agonist compounds, pharmaceutical compositions, use of such compounds in treating immune-mediated diseases, in particular psoriasis and atopic dermatitis, and processes for preparing such compounds.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Jin Z., Li G., He D., Chen J., Zhang Y., Li M., Yao H.. An overview of small-molecule agents for the treatment of psoriasis. Bioorg. Med. Chem. 2025;119:118067. doi: 10.1016/j.bmc.2025.118067. - DOI - PubMed
    1. Abdel-Mageed H. M.. Atopic dermatitis: a comprehensive updated review of this intriguing disease with futuristic insights. Inflammopharmacology. 2025;33:1161–1187. doi: 10.1007/s10787-025-01642-z. - DOI - PMC - PubMed
    1. Yang J., Qiao P., Wang G., Dang E.. The role of aryl hydrocarbon receptor in skin homeostasis: Implications for therapeutic strategies in skin disorders. Cell Biochem. Funct. 2025;43:e70047. doi: 10.1002/cbf.70047. - DOI - PubMed
    1. Hawkes J. E., Al-Saedy M., Bouche N., Al-Saedy S., Drew D. T., Song E. J.. The psoriasis treatment pipeline: An overview and update. Dermatol. Clin. 2024;42:365–375. doi: 10.1016/j.det.2024.02.006. - DOI - PubMed
    1. Sabnis R. W.. Novel aryl hydrocarbon receptor agonists for treating psoriasis and atopic dermatitis. ACS Med. Chem. Lett. 2024;15:2095–2096. doi: 10.1021/acsmedchemlett.4c00537. - DOI - PMC - PubMed

Publication types

LinkOut - more resources