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Editorial
. 2025 May 29;16(6):963-964.
doi: 10.1021/acsmedchemlett.5c00285. eCollection 2025 Jun 12.

Synthesis and Application of Novel Arginine Vasopressin Receptor 1A (AVPR1A) Antagonists

Xin Zhou  1 , Steven H Liang  1
Affiliations
Editorial

Synthesis and Application of Novel Arginine Vasopressin Receptor 1A (AVPR1A) Antagonists

Xin Zhou et al. ACS Med Chem Lett. .

Abstract

Arginine Vasopressin Receptor 1A (AVPR1A) is a member of G-protein-coupled receptors (GPCRs) that binds arginine vasopressin (AVP) and is primarily related to cardiovascular function, glycogenolysis, and social behaviors. This patent describes the synthesis of a series of AVPR1A antagonists and their applications in related disease treatment.

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