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. 1985 Dec 1;56(11):2573-5.
doi: 10.1002/1097-0142(19851201)56:11<2573::aid-cncr2820561106>3.0.co;2-u.

A phase II study of Adriamycin in previously untreated squamous cell carcinoma of the head and neck

M A Cobleigh, J H Hill, P A Gallagher, L J Kukla, T E Lad, D H Shevrin, E L Applebaum, W P McGuire

A phase II study of Adriamycin in previously untreated squamous cell carcinoma of the head and neck

M A Cobleigh et al. Cancer. .

Abstract

Twenty patients with squamous cell carcinoma of the head and neck (SCC H/N) were treated with Adriamycin (doxorubicin) at a dosage of 60 mg/m2 at 3-week intervals. No patient had received surgery, radiation, or chemotherapy before treatment with Adriamycin. Responses were observed in 44% of 18 evaluable tumors. We conclude that Adriamycin is a highly active drug in SCC H/N when no prior treatment has been administered.

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