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. 2025 Jun 18;6(6):CD015343.
doi: 10.1002/14651858.CD015343.pub2.

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Sumeet Gupta  1   2 , Laurence Astill Wright  3   4 , Ogba Onwuchekwa  5 , Nicholas Meader  6 , Ryan Pw Kenny  7 , Rachel Steele  8 , Richard K Morriss  3   9 , Lakshmi Ramana Alla  10 , Nitin Gupta  11
Affiliations

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Sumeet Gupta et al. Cochrane Database Syst Rev. .

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the effectiveness of EWS plus TAU or EWS plus psychological therapy versus TAU alone or psychological treatment (without EWS) independently on time to recurrence of any bipolar episode and hospitalisation, and other clinically relevant outcome measures. To evaluate the effectiveness of intermittent medication used on recognition of EWS without continued mood-stabilising medication versus TAU involving continued mood-stabilising medication on time to recurrence of any bipolar episodes.

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Conflict of interest statement

Sumeet Gupta: no relevant interests; Consultant Psychiatrist, Tees, Esk and Wear Valleys NHS Foundation Trust, Harrogate, UK.

Laurence Astill Wright: no relevant interests, Clinical Research Fellow at University of Nottingham, Nottingham, UK.

Ogba Onwuchekwa: no relevant interests; Senior Registrar working at Minster Ward, Foss Park Hospital, York, UK.

Lakshmi Ramana Alla: no relevant interests; Consultant Forensic Psychiatrist at Stockton Hall Hospital, Priory Group, York, UK.

Richard K Morriss: Magstim Inc. (Grant/Contract), Electromedical Products Inc, Texas (Grant / Contract), Novartis (Independent Contractor – Data And Safety Monitoring); published randomized controlled trials, clinical guidelines, and meta‐analyses, Universities of Manchester, Liverpool, and Nottingham (funding sources: North West Regional Health Authority, Medical Research Council, National Institute for Health Research).

Rachel Steele: none known.

Nitin Gupta: no relevant interests; Consultant Psychiatrist, Gupta Mind Healing and Counselling Centre, Chandigarh, India.

Nicholas Meader: no relevant interests; Deputy Coordinating Editor for Cochrane Common Mental Disorders (closed in March 2023) and was not involved in the editorial decision‐making for this protocol.

Ryan PW Kenny: none known.

Update of

  • doi: 10.1002/14651858.CD015343

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References to other published versions of this review

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