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. 2025 Oct;93(4):285-297.
doi: 10.1111/cod.14824. Epub 2025 Jun 18.

Variability in Paediatric Patch Test Practices Across Europe: A Survey From the European Baseline Series (EBS) Working Party on Behalf of the European Society of Contact Dermatitis (ESCD)

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Variability in Paediatric Patch Test Practices Across Europe: A Survey From the European Baseline Series (EBS) Working Party on Behalf of the European Society of Contact Dermatitis (ESCD)

Olivier Aerts et al. Contact Dermatitis. 2025 Oct.

Abstract

Background: Allergic contact dermatitis (ACD) is an increasingly recognised condition in children and adolescents. However, there is limited knowledge about the different paediatric patch test procedures in European patch test clinics.

Objectives: To map current European paediatric patch test practices, and to relate these to the existing literature, with the aim of guiding the development of a future paediatric patch test guideline, and a corresponding paediatric European baseline series (pEBS).

Materials and methods: In the course of late 2023/early 2024, a standardised paediatric patch test e-mail questionnaire was developed, distributed, and discussed among members of the European Baseline Series (EBS) Working Party of the European Society of Contact Dermatitis (ESCD).

Results: Areas of agreement and discussion were identified regarding patch testing in children of different ages, with and without atopic dermatitis: (contra)indications, choice of allergens and patch test chambers, peculiarities regarding the application and fixation of tests, occlusion and reading times.

Conclusion: Although variability exists in paediatric patch test practices across Europe, there is broad agreement on common procedures, and only a few areas of debate; these findings may be used to inform the development of a future paediatric patch test guideline and pEBS.

Keywords: allergic contact dermatitis; atopic dermatitis; patch test.

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References

    1. A. Goossens and M. A. Morren , “Contact Allergy in Children,” in Contact Dermatitis, ed. J. Johansen , V. Mahler , J. P. Lepoittevin , and P. Frosch (Springer, 2019), https://doi.org/10.1007/978‐3‐319‐72451‐5_48‐1.
    1. A. Belloni Fortina , F. Caroppo , and G. Tadiotto Cicogna , “Allergic Contact Dermatitis in Children,” Expert Review of Clinical Immunology 16, no. 6 (2020): 579–589, https://doi.org/10.1080/1744666X.2020.1777858.
    1. R. Thamm , C. Poethko‐Müller , A. Hüther , and M. Thamm , “Allergic Diseases in Children and Adolescents in Germany. Results of the Cross‐Sectional KiGGS Wave 2 Study and Trends,” Journal of Health Monitoring 3, no. 3 (September 2018): 3–16.
    1. M. Napolitano , G. Fabbrocini , F. Martora , L. Genco , M. Noto , and C. Patruno , “Children Atopic Dermatitis: Diagnosis, Mimics, Overlaps, and Therapeutic Implication,” Dermatologic Therapy 35, no. 12 (December 2022): e15901.
    1. S. E. Jacob , A. Goldenberg , S. Nedorost , J. P. Thyssen , L. Fonacier , and R. Spiewak , “Flexural Eczema Versus Atopic Dermatitis,” Dermatitis 26, no. 3 (2015): 109–115.