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. 2025 Dec 1;110(12):2884-2886.
doi: 10.3324/haematol.2025.288065. Epub 2025 Jun 19.

Olverembatinib in chronic myeloid leukemia: is less actually better?

Affiliations

Olverembatinib in chronic myeloid leukemia: is less actually better?

Maria Agustina Perusini et al. Haematologica. .
No abstract available

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References

    1. Zhang X, Yang Y, Liu B, et al. Optimizing olverembatinib dose in chronic phase chronic myeloid leukemia. Haematologica. 2025;110(12):2986-2996. - PMC - PubMed
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    1. U.S. Food and Drug Administration. Dose Optimization Guidance. 2023.
    1. Copland M. Is there a role for dose modification of TKI therapy in CML? Curr Hematol Malig Rep. 2019;14(4):337-345. - PMC - PubMed
    1. Fassoni AC, Baldow C, Roeder I, Glauche I. Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: a simulation study based on phase III trial data. Haematologica. 2018;103(11):1825-1834. - PMC - PubMed

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