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. 2025 Jun 4:16:1623956.
doi: 10.3389/fneur.2025.1623956. eCollection 2025.

Research progress in intracranial artery dissections over past 25 years: a review and bibliometric analysis

Zixuan Zhou #  1   2   3 , Bingyang Qin #  4 , Yang Chen #  2   3   4 , Ren Li  2   3   5 , Biao Yang  2   3   4 , Ziao Li  2   3   4 , Yongqiang Wu  1   2   3 , Xiaogang Wang  2   3   4 , Xiaolong Guo  2   3   4 , Wenju Zhang  2   3   4 , Yuanli Zhao  6 , Geng Guo  1   2   3   7   8
Affiliations

Research progress in intracranial artery dissections over past 25 years: a review and bibliometric analysis

Zixuan Zhou et al. Front Neurol. .

Abstract

Background: A bibliometric and visual analysis of articles related to intracranial artery dissection (IAD) was performed to reveal the academic developments in this research field, to better assist researchers in reviewing previous research results, exploring current scientific research hotspots and cutting-edge trends, and obtaining a global perspective on IAD research.

Methods: Articles on IAD published from January 1, 2000 to March 15, 2025 were searched, screened, and downloaded using the Web of Science Core Collection (WoSCC). All literature included in the study was analyzed using VOSviewer, CiteSpace and Microsoft Excel.

Results: A total of 1,130 articles were included in the bibliometric analysis from January 2000 to March 2025, with a general upward trend in the number of articles published each year, peaking in 2019 for annual publications. Collaboration network analysis showed that the United States, Japan, and Germany are the more influential countries in the field, with high numbers of published articles, citations, and collaborations with other countries. The journal with the most publications was World Neurosurgery. Lawton MT was the most active author with a cumulative total of 13 articles, while Biller J received the highest number of citations with a cumulative total of 1,033. Keyword analysis of the literature showed that "recanalization "reached the highest intensity of outbreaks, while "thrombectomy "," outcome ", "risk ", and "diagnosis "showed an increase in citations in 2025, indicating that these subjects continue to be of significant interest.

Conclusion: This study explores the evolving research trends and challenges in the area of IAD, presenting a thorough examination of both its historical and current research contexts. It offers valuable direction for future scholarly pursuits. By engaging in comprehensive research and examining various perspectives within the IAD domain, new insights can be uncovered, ultimately facilitating precise diagnosis and effective treatment of the condition.

Keywords: bibliometric analysis; clinical diagnosis and treatments; hotspots; intracranial arterial dissection; pathophysiology.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flowchart for screening publications for this study.
Figure 2
Figure 2
Trends in annual publication volume and citation frequency. (A) Trends in the number of publications, including the annual number of publications and the annual cumulative number of publications, with a polynomial fit to the annual cumulative publication trend. (B) Annual citation frequency curves.
Figure 3
Figure 3
Country/regional cooperation and annual number of publications. (A) Map of geographical distribution of national communications. (B) Change in annual volume of communications for the top 10 countries in terms of volume of communications. (C) Chord chart for country cooperation. (D) Countries of corresponding author.
Figure 4
Figure 4
Institutions and authors co-occurrence visualization network maps. (A) Institutional co-occurrence visualization using Citespace, showing 963 connections from 437 institutions spanning the globe. (B) Collaboration network of 221 authors with more than 3 publications. (C) Collaborative network of 168 authors with more than 20 citations, with the node and label character size representing the number of authors’ publications, and the width of the connecting line representing the density of their collaboration.
Figure 5
Figure 5
Plot of the percentage of core journals and superimposed view of journal publications with citation frequency and impact factor, respectively. (A,B) Number and percentage of core versus non-core journals classified according to Bradford’s law. (C) Superimposed network view of journal publications versus average citation frequency. (D) Overlay network view of journal publications versus journal impact factor.
Figure 6
Figure 6
A dual-map overlay of journals on IAD.
Figure 7
Figure 7
Cluster network analysis of references in the IAD research field from 2000 to 2024. (A) Visual analysis of the clustering network of co-cited literature. The top 15 largest citation clusters are shown. (B) Timeline view of co-cited references. Each horizontal line represents a cluster, with smaller labeled numbers and larger node sizes reflecting co-citation frequency, while links indicate co-citation relationships. The colors of the nodes and lines represent different citation years. (C) Top 25 references with the strongest citation burst.
Figure 8
Figure 8
Visualization graph of keyword co-occurrence networks and evolutionary trends. (A) Co-occurrence network and clustering diagram of keywords. A total of 3,174 keywords, 154 with more than 5 occurrences were selected for visualization and analysis. (B) Stacked plots of keyword frequency versus time of occurrence. (C) Trends in research hotspots over time. (D) The top 25 keywords with the strongest bursts.
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References

    1. Arning C, Hanke-Arning K, Eckert B. The clinical features of dissection of the cervical brain-supplying arteries. Dtsch Arztebl Int. (2022) 119:581–7. doi: 10.3238/arztebl.m2022.0238, PMID: - DOI - PMC - PubMed
    1. Mizutani T, Miki Y, Kojima H, Suzuki H. Proposed classification of nonatherosclerotic cerebral fusiform and dissecting aneurysms. Neurosurgery. (1999) 45:253–9. doi: 10.1097/00006123-199908000-00010 - DOI - PubMed
    1. Debette S, Compter A, Labeyrie MA, Uyttenboogaart M, Metso TM, Majersik JJ, et al. Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection. Lancet Neurol. (2015) 14:640–54. doi: 10.1016/s1474-4422(15)00009-5, PMID: - DOI - PubMed
    1. Li S, Yan B, Kaye A, Mitchell P, Dowling R, Collins M, et al. Prognosis of intracranial dissection relates to site and presenting features. J Clin Neurosci. (2011) 18:789–93. doi: 10.1016/j.jocn.2010.11.006, PMID: - DOI - PubMed
    1. Chen H, Li Z, Luo B, Zeng J. Anterior cerebral artery dissection diagnosed using high-resolution MRI. Neurology. (2015) 85:481. doi: 10.1212/wnl.0000000000001813, PMID: - DOI - PubMed

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