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. 2025 Jun 18;18(6):1071-1076.
doi: 10.18240/ijo.2025.06.13. eCollection 2025.

Evaluation of the risk factors for rhegmatogenous retinal detachment associated with choroidal detachment from the viewpoint of treatment patterns: a retrospective study

Kai Gao  1 , Zi-Ye Chen  1 , Zhuang-Ling Lin  1 , Ya-Ping Liu  1 , Bao-Yi Liu  1 , Yuan Ma  1 , Zi-Tong Chen  1 , Rebiya Tuxun  1 , Lan Jiang  1 , Zhuo-Jun Xu  1 , Chin-Ling Tsai  1 , Kun-Bei Lai  1 , Tao Li  1
Affiliations

Evaluation of the risk factors for rhegmatogenous retinal detachment associated with choroidal detachment from the viewpoint of treatment patterns: a retrospective study

Kai Gao et al. Int J Ophthalmol. .

Abstract

Aim: To compare the proportion of rhegmatogenous retinal detachment (RRD) associated with choroidal detachment (RRDCD) in the emergency surgery group with the routine inpatient surgery group and determine risk factors for RRDCD.

Methods: A total of 694 patients (694 eyes) diagnosed with RRD in the emergency surgery (the median duration of RRD was 5d) group were included from the Department of Ophthalmic Emergency, and 692 patients (eyes) in the routine inpatient surgery group (the median duration was 15d) were selected randomly from the Ocular Fundus Department. Demographics, refractive status, macular status, lens status, extent of retinal detachment, number of retinal breaks, duration of symptoms before surgery, and the incidence of RRDCD were compared. A logistic regression analysis was used to determine potential risk factors for RRDCD.

Results: Compared to the routine inpatient surgery group, the emergency surgery group had a significant less median time to surgery (P<0.001) and a decreased proportion of RRDCD (2.88% vs 10.84%, P<0.001). Logistic regression analysis revealed that a prolonged duration of RRD [OR 3.51, 95% confidence interval (CI) 1.98-6.23], pseudophakia/aphakia status [OR 2.74, 95%CI (1.50-4.98)], multiple retinal breaks [OR 1.67, 95%CI (1.03-2.70)], and a substantial extent of RRD [OR 11.58, 95%CI (7.12-18.84)] were independent risk factors for RRDCD.

Conclusion: Emergency surgical pattern of RRD demonstrates a lower incidence of RRDCD. The adoption of an expedited surgical approach has the potential to reduce the duration of RRD, possibly correlating with a decreased risk of RRDCD development.

Keywords: ophthalmic emergency; rhegmatogenous retinal detachment; rhegmatogenous retinal detachment with choroidal detachment.

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Conflict of interest statement

Conflicts of Interest: Gao K, None; Chen ZY, None; Lin ZL, None; Liu YP, None; Liu BY, None; Ma Y, None; Chen ZT, None; Tuxun R, None; Jiang L, None; Xu ZJ, None; Tsai CL, None; Lai KB, None; Li T, None.

Figures

Figure 1
Figure 1. Flow chart showing the process for determining eligibility for inclusion in the inpatient surgery group between October 2019 and December 2020.
Figure 2
Figure 2. Flow chart showing the process for determining eligibility for inclusion in the emergency surgery group between January 2021 and March 2022.
Figure 3
Figure 3. Binary logistic regression analysis of risk factors for RRDCD
OR values greater than 1 indicating positive relationship, and OR values less than 1 indicating negative relationship; aP<0.05, bP<0.001. RRDCD: Rhegmatogenous retinal detachment associated with choroidal detachment; OR: Odds ratio.
See this image and copyright information in PMC

References

    1. Wu ZF, Ding NN, Yu MX, et al. Identification of potential biomarkers for rhegmatogenous retinal detachment associated with choroidal detachment by vitreous iTRAQ-based proteomic profiling. Int J Mol Sci. 2016;17(12):2052. - PMC - PubMed
    1. Li ZH, Li YH, Huang XH, et al. Quantitative analysis of rhegmatogenous retinal detachment associated with choroidal detachment in Chinese using UBM. Retina. 2012;32(10):2020–2025. - PubMed
    1. Li PP, Li L, Wu JH. The effect of steroid intervention before vitrectomy for rhegmatogenous retinal detachment associated with choroidal detachment: a meta-analysis and systematic review. Curr Eye Res. 2024;49(10):1005–1011. - PubMed
    1. Seelenfreund MH, Kraushar MF, Schepens CL, et al. Choroidal detachment associated with primary retinal detachment. Arch Ophthalmol. 1974;91(4):254–258. - PubMed
    1. Luo SS, Xu HY, Yang LF, et al. Quantitative proteomics analysis of human vitreous in rhegmatogenous retinal detachment associated with choroidal detachment by data-independent acquisition mass spectrometry. Mol Cell Biochem. 2022;477(6):1849–1863. - PubMed

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