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Review
. 2025 Jun 17;20(1):20251117.
doi: 10.1515/biol-2025-1117. eCollection 2025.

Polyphenolic spectrum of cornelian cherry fruits and their health-promoting effect

Tunde Jurikova  1 , Nela Skowronkova  2 , Magdalena Zvonkova  2 , Jana Orsavova  3 , Sezai Ercisli  4 , Libor Dokoupil  5 , Katarina Fatrcova-Sramkova  6 , Anna Adamkova  2 , Jiri Mlcek  2
Affiliations
Review

Polyphenolic spectrum of cornelian cherry fruits and their health-promoting effect

Tunde Jurikova et al. Open Life Sci. .

Abstract

Although cornelian cherry is an underutilized fruit species, its fruits have a high biological value due to valuable biologically active substances, especially polyphenols. The total content of polyphenols accounts for 37% of all the bioactive substances examined. Flavonols, anthocyanins, flavan-3-ols, and phenolic acids represent the main groups of phenolic compounds present and thanks to these compounds, cornelian cherry fruits possess mainly antioxidant, anti-inflammatory, antimicrobial, metabolic, antidiabetic, cardioprotective, and anticancer effects. This review summarizes new research aimed at popularizing this lesser-known species not only for direct consumption but also for further processing.

Keywords: Cornus mas; anti-inflammatory; anticancer effect; antidiabetic; antimicrobial; metabolic; polyphenols.

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Conflict of interest statement

Conflict of interest: Authors state no conflict of interest.

Figures

Figure 1
Figure 1
The overview of the main flavonoids of C. mas fruit.
Figure 2
Figure 2
The overview of the main anthocyanidins in C. mas fruit.
See this image and copyright information in PMC

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