Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 May 19;17(5):e84401.
doi: 10.7759/cureus.84401. eCollection 2025 May.

Exploring the Link Between Caffeine Intake, Sleep Quality, and Restless Legs Syndrome Among Medical Students

Affiliations

Exploring the Link Between Caffeine Intake, Sleep Quality, and Restless Legs Syndrome Among Medical Students

Bhavna Singla et al. Cureus. .

Abstract

Background Medical students face increased threats to their sleep quality and lifestyle health because academic stress and unpredictable class hours create these challenges. Medical students commonly use too much caffeine as a stress management tool, but research lacks data about how caffeine affects both sleep quality and restless legs syndrome (RLS) symptoms. Methods The study utilized a research design combining cross-sectional analysis and correlation assessment with a participant group of 300 medical students ranging from 18 to 30 years old. Data was collected from January to March 2025. The Caffeine Consumption Questionnaire, combined with the Pittsburgh Sleep Quality Index (PSQI) and Restless Legs Syndrome Symptom Severity Scale, enabled researchers to collect necessary data. IBM SPSS Statistics for Windows, version 26 (IBM Corp., Armonk, NY) served as the platform to perform all statistical assessments through descriptive statistics, ANOVA tests, chi-square tests, correlation analysis, and multiple regression procedures. Results The medical students among the surveyed sample of 300 showed 237 participants (79%) caffeine consumption, while 78 participants (26%) consumed it nightly. Studies revealed that RLS symptoms affected 34 participants (11.2%) of participants as increased caffeine consumption resulted in milder RLS (r = -0.383, p < 0.01) yet negatively impacted sleep quality (r = 0.197, p < 0.01). The students who consumed caffeine in the morning experienced the highest sleep quality and the lowest severity of RLS symptoms (r = -0.266, p < 0.01). Additionally, poor sleep deteriorated RLS symptoms. Conclusion Higher caffeine use minimizes the reported intensity of RLS symptoms but leads to diminished sleep quality, particularly when coffee is taken late in the day. The combination of poor sleep and RLS symptoms creates a continuous worsening effect that persists across the cycle. Medical students' overall health and academic performance depend on specific intervention methods that teach proper sleep habits and caffeine consumption.

Keywords: caffeine consumption; lifestyle factors; medical students; restless legs syndrome (rls); sleep quality.

PubMed Disclaimer

Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Institutional Review Board, NeuroWave Research Center, Islamabad issued approval IRB-2025-0017. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Similar articles

References

    1. Sleep quality: an evolutionary concept analysis. Nelson KL, Davis JE, Corbett CF. https://doi.org/10.1111/nuf.1265. Nurs Forum. 2022;57:144–151. - PubMed
    1. Kline CE. Encyclopedia of Behavioral Medicine. Cham: Springer; 2020. Sleep quality; pp. 2064–2066.
    1. Sleep quality in medical students: a comprehensive meta-analysis of observational studies. Rao WW, Li W, Qi H, et al. https://doi.org/10.1007/s11325-020-02020-5. Sleep Breath. 2020;24:1151–1165. - PubMed
    1. Internet addiction and sleep quality among medical students during the COVID-19 pandemic: A multinational cross-sectional survey. Tahir MJ, Malik NI, Ullah I, et al. https://doi.org/10.1371/journal.pone.0259594 PLoS One. 2021;16:0. - PMC - PubMed
    1. The prevalence and association of stress with sleep quality among medical students. Almojali AI, Almalki SA, Alothman AS, Masuadi EM, Alaqeel MK. https://doi.org/10.1016/j.jegh.2017.04.005. J Epidemiol Glob Health. 2017;7:169–174. - PMC - PubMed

LinkOut - more resources