Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun 18;15(2):99554.
doi: 10.5500/wjt.v15.i2.99554.

Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience

Biagio Pinchera  1 , Rosa Carrano  2 , Elisa Schettino  2 , Alessia D'Agostino  3 , Emilia Trucillo  3 , Federica Cuccurullo  3 , Fabrizio Salemi  2 , Amerigo Piccione  2 , Ivan Gentile  3
Affiliations

Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience

Biagio Pinchera et al. World J Transplant. .

Abstract

Background: Urinary tract infections (UTIs) in kidney transplant patients are a challenge.

Aim: To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI.

Methods: We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients.

Results: From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.

Conclusion: Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.

Keywords: Empiric therapy; Kidney transplant; Multidrug-resistant germ; Solid organ transplant recipient; Urinary tract infections.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: The authors declare no conflicts of interest.

References

    1. Vidal E, Cervera C, Cordero E, Armiñanzas C, Carratalá J, Cisneros JM, Fariñas MC, López-Medrano F, Moreno A, Muñoz P, Origüen J, Sabé N, Valerio M, Torre-Cisneros J Study Group of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Infectious Diseases, Clinical Microbiology (SEIMC); Spanish Network for Research in Infectious Diseases (REIPI) Management of urinary tract infection in solid organ transplant recipients: Consensus statement of the Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Network for Research in Infectious Diseases (REIPI) Enferm Infecc Microbiol Clin. 2015;33:679.e1–679.e21. - PubMed
    1. Jamil S, Zafar MN, Siddiqui S, Ayub S, Rizvi AU. Recurrent Urinary Tract Infections in Renal Transplant Recipients: Risk Factors and Outcomes in Low-resource Settings. Saudi J Kidney Dis Transpl. 2022;33:761–773. - PubMed
    1. Alangaden G. Urinary tract infections in renal transplant recipients. Curr Infect Dis Rep. 2007;9:475–479. - PubMed
    1. Takai K, Aoki A, Suga A, Tollemar J, Wilczek HE, Naito K, Groth CG. Urinary tract infections following renal transplantation. Transplant Proc. 1998;30:3140–3141. - PubMed
    1. Britt NS, Hagopian JC, Brennan DC, Pottebaum AA, Santos CAQ, Gharabagi A, Horwedel TA. Effects of recurrent urinary tract infections on graft and patient outcomes after kidney transplantation. Nephrol Dial Transplant. 2017;32:1758–1766. - PubMed

LinkOut - more resources