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. 2025 Jun 4:12:1564843.
doi: 10.3389/fsurg.2025.1564843. eCollection 2025.

Anticipating postoperative complications in hepatobiliary surgery: procalcitonine as predictive factor

Shouwen Zhao  1 , Yuanyuan Song  1 , Le Zhang  2 , Sunan Shi  2 , Jie Li  2 , Yuping Ma  1 , Yong Liao  1 , Zhongguang Zhen  1
Affiliations

Anticipating postoperative complications in hepatobiliary surgery: procalcitonine as predictive factor

Shouwen Zhao et al. Front Surg. .

Abstract

Background and aims: Few studies have indicated that procalcitonin has a potential role in anticipating postoperative complications of hepatic surgery. Here, we focused on validating the relationship between posthepatectomy and serum procalcitonin as short-term prognostic factors.

Methods: Data from 52 patients who underwent hepatectomy (partial) due to hepatocellular carcinoma from June 2018 to July 2023 were enrolled to evaluate the risk factors related to post-hepatectomy complications, especially post-hepatectomy liver failure and 30-day survival.

Results: 52 patients were included in the study, and their data was analyzed for PCT. 21 showed raised PCT (>1 ng/ml). Results showed a significant association of PCT with post-hepatectomy liver failure, and the same is associated with 30-day mortality in ICU-admitted patients.

Conclusion: Elevated PCT levels in patients after hepatic surgery are associated with poor prognosis and could be used as a potential predictive factor.

Keywords: hepatectomy; liver failure; liver failure prognostic factor; postoperative complications; procalcitonin.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(a) Mean, median, and mode of different PCT values among the patients; (b) Distribution of PCT levels >1 ng/ml groups. Statistical comparison was performed using the chi-square test.
Figure 2
Figure 2
PCT level in all 52 patients.
Figure 3
Figure 3
Number of patients with different comorbidities.
Figure 4
Figure 4
Short-term mortality in both groups.
See this image and copyright information in PMC

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