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Review
. 2025 Jun 19.
doi: 10.1007/s12265-025-10617-y. Online ahead of print.

Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment

Sun Qingpiao  1 , Zhang Yi  2
Affiliations
Review

Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment

Sun Qingpiao et al. J Cardiovasc Transl Res. .

Abstract

Exosomes are small vesicles secreted by a variety of cells surrounded by a lipid bilayer membrane and containing a variety of biomolecules, of which microRNAs (miRNAs) are the most abundant. Exosomal miRNAs are involved in the development of cardiovascular diseases(CVD), and their unique biological properties make them expected to be effective targets for the treatment of CVD. This article reviews the biological characteristics, expression, and mechanism of action of exosomes and exosomal miRNAs in CVD, as well as their potential as biomarkers in the diagnosis, treatment, and prognostic assessment of CVD, to provide new ideas in the field of CVD medicine.

Keywords: Biomarker; Cardiovascular disease; Drug carrier; Exosomal miRNAs.

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Conflict of interest statement

Declarations. Ethics Approval: Not applicable. Consent for Publication: Not applicable. Conflict of Interest: The authors declare that they have no conflict of interest.

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