Cardiac LIM Protein, Kidney Fibrosis, and Vascular Change after Acute Cardiorenal Syndrome

Affiliations

¹ Department of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Portland, Oregon.
² Department of Pediatrics, University of Washington, Seattle, Washington.
³ Center for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington.
⁴ Division of Nephrology, and Hypertension, Department of Medicine, Keck School of Medicine, University of Southern California. Los Angeles, California.
⁵ Department of Pathology, Oregon Health and Science University, Portland, Oregon.
⁶ Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
⁷ Institute for the Advanced Study of Human Biology, Kyoto University, Kyoto, Japan.
⁸ Operative Care Division, Portland Veterans Administration Medical Center, Portland, Oregon.

Yoshio Funahashi et al. J Am Soc Nephrol. 2025.

. 2025 Jun 19.

doi: 10.1681/ASN.0000000774. Online ahead of print.

¹ Department of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Portland, Oregon.
² Department of Pediatrics, University of Washington, Seattle, Washington.
³ Center for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington.
⁴ Division of Nephrology, and Hypertension, Department of Medicine, Keck School of Medicine, University of Southern California. Los Angeles, California.
⁵ Department of Pathology, Oregon Health and Science University, Portland, Oregon.
⁶ Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
⁷ Institute for the Advanced Study of Human Biology, Kyoto University, Kyoto, Japan.
⁸ Operative Care Division, Portland Veterans Administration Medical Center, Portland, Oregon.

No abstract available

Keywords: CKD; cardiovascular events; cell and transport physiology; endocytosis; hypertension and cardiorenal disorders.

References

1. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1736–1788. doi: 10.1016/s0140-6736(18)32203-7 - DOI
1. Schuett K, Marx N, Lehrke M. The cardio-kidney patient: epidemiology, clinical characteristics and therapy. Circ Res. 2023;132(8):902–914. doi: 10.1161/circresaha.122.321748 - DOI
1. Ronco C, Haapio M, House AA, Anavekar N, Bellomo R. Cardiorenal syndrome. J Am Coll Cardiol. 2008;52(19):1527–1539. doi: 10.1016/j.jacc.2008.07.051 - DOI
1. Ronco C, McCullough PA, Anker SD, et al. Cardiorenal syndromes: an executive summary from the consensus conference of the Acute Dialysis Quality Initiative (ADQI). Contrib Nephrol. 2010;165:54–67. doi: 10.1159/000313745 - DOI
1. Ronco C, Di Lullo L. Cardiorenal syndrome in Western countries: epidemiology, diagnosis and management approaches. Kidney Dis (Basel). 2017;2(4):151–163. doi: 10.1159/000448749 - DOI