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. 2025 Dec 1:390:119719.
doi: 10.1016/j.jad.2025.119719. Epub 2025 Jun 18.

Benchmarking empirical severity for the Yale-Brown Obsessive Compulsive Scale-Second Edition

Collaborators, Affiliations

Benchmarking empirical severity for the Yale-Brown Obsessive Compulsive Scale-Second Edition

Caitlin M Pinciotti et al. J Affect Disord. .

Abstract

The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is considered the primary instrument for assessing the presence and severity of obsessive-compulsive disorder (OCD). Conceptual and empirical critiques inspired the development of an updated version of the instrument, the Yale-Brown Obsessive Compulsive Scale-Second Edition (Y-BOCS-II), with a higher ceiling of OCD severity to better differentiate between severe and the most debilitating OCD presentations, among other revisions. The Y-BOCS-II has demonstrated sound psychometric properties across diverse samples. Empirically derived severity benchmarks have been proposed for the original Y-BOCS, yielding somewhat different ranges than what has been commonly used in clinical and research settings, yet severity benchmarks for the Y-BOCS-II have yet to be established. Using a diverse, pooled sample of 2982 children and adults with OCD or obsessive-compulsive and related concerns across 13 countries, receiver-operating characteristic (ROC) analyses yielded severity benchmarks that largely mirrored the original Y-BOCS at the lower range of scores and extended the previously established benchmarks at the higher range of scores, owing to the increased ceiling of the instrument. The optimal benchmark ranges were determined as: non-/sub-clinical (0-14), mild (15-21), moderate (22-34), severe (35-50). Similar benchmarks were present across sex and age groups, and their accuracy was adequate in both a holdout sample and an independent sample of OCD patients from China (n = 78). Limitations and implications for the use of the Y-BOCS-II in clinical and research settings are discussed.

Keywords: Assessment; Obsessive-compulsive disorder; Receiver-operating characteristic analyses; Severity benchmarks; Yale-Brown Obsessive Compulsive Scale-Second Edition.

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Conflict of interest statement

Declaration of competing interest Dr. Rodriguez (in the last three years) has been a consultant for Biohaven Inc., Osmind, and Biogen; received research grant support from Biohaven Inc.; received royalties from American Psychiatric Association Publishing; and received a stipend from APA Publishing for her role as Deputy Editor at The American Journal of Psychiatry and a stipend for her role as Deputy Editor of Neuropsychopharmacology. Dr. Arnold receives research funding from Biohaven Inc., Canadian Institute for Health Research, Ontario Brain Institute, Genome Canada, and Alberta Children's Hospital Research Foundation. Dr. Martínez-González receives funding from NIH and FDA. She is a consultant with Abbvie, Sage Pharmaceuticals and SAMHSA. Dr. Goodman receives research fundings from NIH, Biohaven, and the McNair Foundation and consulting fees from Biohaven. He receives royalties from Proem. Dr. Storch reports receiving research funding to his institution from the Ream Foundation, International OCD Foundation, and NIH. He is a consultant for Brainsway and Biohaven Pharmaceuticals. He owns stock less than $5000 in NView. He receives book royalties from Elsevier, Wiley, Oxford, American Psychological Association, Guildford, Springer, Routledge, and Jessica Kingsley. Dr. Cervin receives research support from the Kavli Foundation, the Swedish Research Council for Health, Working Life and Welfare, the Lindhaga Foundation, Stiftelsen Clas Grochinskys Minnesfond, the Crown Princess Lovisa's Association, the Kamprad Family Foundation, Fonden för Psykisk Hälsa, and Skåne University Hospital's Foundations and Donations; and financial compensation from Springer for editorial work outside of the submitted work. All other authors report no financial disclosures.

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