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Randomized Controlled Trial
. 2025 Jun 21;145(1):349.
doi: 10.1007/s00402-025-05962-1.

Comparison of periarticular injection and low-concentration high-volume suprainguinal fascia Iliaca plane block in total knee arthroplasty: a randomized prospective study

Mehmet Cenk Turgut  1 , Elif Oral Ahiskalioglu  1 , Yunus Emre Karapinar  1 , Ela Medetoglu Koksal  1 , Cagatay Engin  1 , Erkan Cem Celik  1 , Muhammed Enes Aydin  2 , Ahmet Murat Yayik  1
Affiliations
Randomized Controlled Trial

Comparison of periarticular injection and low-concentration high-volume suprainguinal fascia Iliaca plane block in total knee arthroplasty: a randomized prospective study

Mehmet Cenk Turgut et al. Arch Orthop Trauma Surg. .

Abstract

Background: The suprainguinal fascia iliaca plane block (SFIPB) has been used effectively for postoperative analgesia in hip surgeries due to its extensive dermatomal coverage. This technique may also serve as an alternative in knee surgeries. However, studies investigating the use of SFIPB in total knee arthroplasty (TKA) are limited. This study evaluates the efficacy of SFIPB compared to periarticular infiltration (PAI) in TKA, focusing on postoperative opioid consumption, pain scores, motor function, and rehabilitation outcomes.

Methods: This randomized controlled trial included 70 patients undergoing TKA, allocated to either the SFIPB group or the PAI group. Postoperative pain management was standardized across groups using patient-controlled fentanyl analgesia. Primary outcomes included opioid consumption over 48 h, and secondary outcomes assessed pain scores, quadriceps strength, mobilization times, range of motion (ROM), and rehabilitation test results.

Results: SFIPB resulted in significantly reduced opioid consumption at 24 and 48 h compared to PAI (p < 0.001). Pain scores assessed via visual analogue scale (VAS) were lower in the SFIPB group, particularly for anterior knee pain during rest and movement (p < 0.05). SFIPB also demonstrated superior rehabilitation outcomes, with improved quadriceps strength (p = 0.002) and better performance on the Time Up and Go (TUG) test. Both groups reported minimal side effects, but opioid-related nausea and vomiting were less frequent in the SFIPB group.

Conclusion: The use of SFIPB with a dilute, high-volume local anesthetic was superior to PAI by reducing opioid consumption and opioid-related side effects without impairing motor function or patient mobilization. This highlights its potential as an effective analgesic technique in TKA.

Keywords: Periarticular infiltration; Suprainguinal fascia Iliaca plane block; Total knee arthroplasty.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
CONSORT diagram of the study
Fig. 2
Fig. 2
a) Sono anatomic illustration of suprainguinal fascia iliaca plane block with needle and local anesthetic distribution. (LA: local anesthetic) b) Ultrasound image illustrating the suprainguinal fascia iliaca plane block puncture trajectory. c) Patient-probe and needle orientation for block application
See this image and copyright information in PMC

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