doi: 10.1016/0014-5793(85)80002-8.
25-Hydroxyvitamin D3 3-sulphate is a major circulating form of vitamin D in man
- PMID: 4054307
- DOI: 10.1016/0014-5793(85)80002-8
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25-Hydroxyvitamin D3 3-sulphate is a major circulating form of vitamin D in man
FEBS Lett.
.
Free article
Abstract
25-Hydroxyvitamin D3 3 beta-sulphate has been identified in human plasma. The compound was isolated by anion-exchange chromatography and following hydrolysis it was characterized by high-performance liquid chromatography and gas chromatography-mass spectrometry. The mean concentration of sulphated 25-hydroxyvitamin D3 in plasma from 60 patients was 16.7 +/- 7.1 ng/ml and the levels often exceeded those of the corresponding free compound. The study also shows that unconjugated 25-hydroxyvitamin D3 is not readily sulphated by man in vivo.
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