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Review
. 2025 Jul;36(3):365-373.
doi: 10.1016/j.nec.2025.03.005. Epub 2025 Apr 28.

Fever in the Neurocritically Ill Patient

Affiliations
Review

Fever in the Neurocritically Ill Patient

Ryan Kitagawa et al. Neurosurg Clin N Am. 2025 Jul.

Abstract

Fever among patients in the neurologic intensive care unit (ICU) is common and is associated with worse outcomes. Such fevers are likely due to infection or neurologic injury. Measures to control fever include pharmacologic and mechanical methods, and though such measures are effective, the literature is unclear on whether these interventions improve patient outcomes. The choice of intervention should be carefully considered for febrile neuro ICU patients and weighed against potential adverse effects. Further research on how temperature management affects outcomes in this population is needed to better inform management.

Keywords: Fever; Infection; Neurogenic fever; Neurologic intensive care unit; Neurosurgery.

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Conflict of interest statement

Disclosure The authors have no disclosures.

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