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Multicenter Study
. 2025 Sep;44(9):2219-2230.
doi: 10.1007/s10096-025-05188-4. Epub 2025 Jun 23.

Incidence trends and epidemiology of invasive device-associated bacteremia in French nursing home residents, 2020-2024: Insights from the SPIADI Prospective Multicenter Study

members of the SPIADI Network; Maris Dussartre  1 , Nicolas Duflot  1 , Anne-Sophie Valentin  1 , Mathilde Farizon  1 , Florent Goube  1 , Nathalie van der Mee-Marquet  2
Affiliations
Multicenter Study

Incidence trends and epidemiology of invasive device-associated bacteremia in French nursing home residents, 2020-2024: Insights from the SPIADI Prospective Multicenter Study

members of the SPIADI Network et al. Eur J Clin Microbiol Infect Dis. 2025 Sep.

Abstract

Healthcare-associated bacteremia is associated with increased morbidity and mortality. In nursing homes, these infections remain under-documented. We investigated invasive device-associated bacteremia in residents. We analyzed bacteremias acquired in nursing homes using data from a national surveillance program conducted between 2020 and 2024, involving 1,233 French healthcare institutions. A total of 2,117 bacteremias acquired in the nursing home were recorded. The main sources of infection were the urinary tract (52.1%) and the respiratory tract (11.9%). An invasive device was involved in 20.0% of cases, primarily urinary catheters (386 cases), while bacteremia related to intravascular devices was rare (38 cases). Enterobacterales (64.0%) and Staphylococcus aureus (14.6%) were the most frequently identified pathogens, with multidrug-resistant bacteria detected in 15.2% of nursing home-acquired bacteremias. The incidence rate was 0.009 per 1,000 resident-days, remaining stable over the study period. The study highlights the burden of bacteremias in nursing homes and underscores the importance of targeted infection prevention measures, particularly in relation to urinary catheter management, and long-term intravascular central lines.

Keywords: Central line associated bacteremia; Central venous catheter; Implantable port catheter; Intravascular devices-related bacteremia; Nursing home; Peripherally inserted central catheter; Urinary devices-related bacteremia.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: All experiments were performed in accordance with relevant guidelines and regulations. The study was conducted within the framework of the national agency Santé Publique France and the national program for the prevention of healthcare-associated infections (National Health Strategy 2018–2022), which advocates for regular evaluation of healthcare professionals'practices by local infection control teams. All work related to this program has been authorized by the CNIL (National Commission on Informatics and Liberties; file 2212596 dated March 27, 2019). Locally, participation in the study required written commitment from the hospital director and the infection control team leader. The commiment charters were collected at the national level by the SPIADI team. In the departments where the study was conducted, the professionals (HCWs) and patients were informed about the study (observational component, microbiological component, and impact study of the proposed training). Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Distribution of the microorganisms associated with the 2,117 nursing home-acquired bacteraemia cases (2020–2024)
See this image and copyright information in PMC

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