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. 2025 Jun 10;19(2 Suppl):132S-154S.
doi: 10.1177/15598276251325485. eCollection 2025 Jul.

Executive Summary of Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine

Affiliations

Executive Summary of Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine

Richard M Rosenfeld et al. Am J Lifestyle Med. .

Abstract

This executive summary highlights evidence-based recommendations for using lifestyle interventions in the treatment and remission of type 2 diabetes (T2D) and prediabetes in adults. The summary and guideline are intended for any clinician or healthcare professional in a community or non-inpatient healthcare setting involved in managing non-pregnant adults with T2D, prediabetes or a history of gestational diabetes mellitus (GDM). The purpose of this executive summary is to provide a succinct overview of the key action statements (recommendations) from Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline from the American College of Lifestyle Medicine. This is the first diabetes guideline to emphasize lifestyle interventions as the foundation of management and is also the first to focus on all six pillars of lifestyle medicine (plant-predomination nutrition, regular physical activity, restorative sleep, stress reduction, social connectedness, and avoiding risky substances), including behavior change strategies. This summary is not intended to substitute for the full guideline, which should be read before taking the recommended actions. The guideline on which this summary is based was developed with a priori methodology that has been previously published, refined, and used in over 20 multidisciplinary, trustworthy, and evidence-based national guidelines. The guideline development group included 20 members representing consumers, advanced practice nursing, cardiology, clinical pharmacology, behavioral medicine, endocrinology, family medicine, lifestyle medicine, nutrition and dietetics, health education, health and wellness coaching, sleep medicine, sports medicine, and obesity medicine. We developed 14 key action statements and associated evidence profiles, each with a distinct quality improvement goal in the context of lifestyle interventions for T2D. Strong recommendations were made regarding advocacy for lifestyle interventions; assessing baseline lifestyle habits; establishing priorities for lifestyle change; prescribing aerobic and muscle strength physical activity; reducing sedentary time; identifying sleep disorders; prescribing nutrition plans for prevention and treatment; promoting peer/familial support and social connections; counseling regarding tobacco, alcohol, and recreational drugs, and establishing a plan for continuity of care. Recommendations were made regarding identifying the need for psychological interventions and for adjusting (deprescribing) pharmacologic therapy. We include numerous tables and figures to facilitate implementation, a plain-language summary for consumers, and an executive summary for clinicians as separate publications. Although not a substitute for the full clinical practice guideline, this executive summary can provide insight into the key guideline recommendations, to whom they apply, and to how they might alter care. These recommendations offer detailed, explicit, and evidence-based strategies for successful lifestyle behavior change, making them relevant not only to our guideline but to other guidelines and standards that advocate for lifestyle change in managing adults with T2D.

Keywords: behavioral medicine; clinical practice guideline (CPG); evidence-based medicine; gestational diabetes mellitus; health coaching; lifestyle interventions; lifestyle medicine; nutrition; prediabetes; primary care integration; social determinants of health; type 2 diabetes.

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Conflict of interest statement

The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Richard M. Rosenfeld: Non-Financial—Sr. Advisor for Medical Society Relations, ACLM; Chief Medical Officer, ABLM; employee- American College of Lifestyle Medicine; Jonathan P. Bonnet: Published two editions of the Lifestyle Medicine Handbook and the Medical Fitness Bible. Co-lead of the ACLM’s Board Review Course. Serves on the American Board of Lifestyle Medicine. Recipient of multiple research grants from the Ardmore Institute of Health in conducting Teaching Kitchen research at Emory University. Jane F. Kapustin: Consulting Fee—Speaker for Sanofi/Provention Bio (Type 1 D prevention) National and regional speaker for NP and other medical associations. Micaela C. Karlsen: salaried employee—American College of Lifestyle Medicine. Dawn R. Noe: Consulting Fee—Speaker for Lifescan Diabetes, Diabetes Advisor for Medtronic; Salary—private practice nutrition coaching business. Kara L. Staffier: salaried employee—American College of Lifestyle Medicine.

References

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