Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 May 30;5(4):100543.
doi: 10.1016/j.bpsgos.2025.100543. eCollection 2025 Jul.

Remember Me? Adolescent Thalamic Inhibition Leads to Deficits in Cortical Maturation and Social Memory

Affiliations

Remember Me? Adolescent Thalamic Inhibition Leads to Deficits in Cortical Maturation and Social Memory

Isabel Bravo et al. Biol Psychiatry Glob Open Sci. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Summary of the behavioral and physiological consequences of inhibiting the mouse mediodorsal thalamus during early adolescence. DREADD, designer receptor activated by designer drugs; MD, mediodorsal thalamus; NA, not analyzed; PFC, prefrontal cortex; PPR, paired-pulse ratio; PV, parvalbumin; SST, somatostatin.

Similar articles

References

    1. Penn D.L., Sanna L.J., Roberts D.L. Social cognition in schizophrenia: An overview. Schizophr Bull. 2008;34:408–411. - PMC - PubMed
    1. Gogtay N., Giedd J.N., Lusk L., Hayashi K.M., Greenstein D., Vaituzis A.C., et al. Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci U S A. 2004;101:8174–8179. - PMC - PubMed
    1. Keshavan M.S., Anderson S., Pettegrew J.W. Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited. J Psychiatr Res. 1994;28:239–265. - PubMed
    1. Yang S.S., He Q., Gu X., Liu S., Ke W., Chen L., et al. Transient Inhibition of the Mediodorsal Thalamus During Early Adolescence Induces Hypofrontality and Social Memory Deficits in Young Adulthood. Biol Psychiatry Glob Open Sci. 2025;5 - PMC - PubMed
    1. Hensch T.K. Critical period regulation. Annu Rev Neurosci. 2004;27:549–579. - PubMed

LinkOut - more resources