doi: 10.1159/000153581.
Plasma cholinesterase variants. Family studies of the E1k gene
- PMID: 4054903
- DOI: 10.1159/000153581
Item in Clipboard
Plasma cholinesterase variants. Family studies of the E1k gene
Hum Hered.
1985.
Abstract
The use of RO2-0683 as differential inhibitor has shown that 13% of 181 heterozygotes, believed to be E1uE1a, are in fact E1aE1k. The results indicate that slightly more than 1% of the British population could be homozygote E1kE1k. Analysis of 47 families segregating the E1aE1k phenotype in more than 2 blood relatives is restricted by the inability to differentiate the genotypes E1uE1k and E1kE1k from E1uE1u and E1uE1f.
Similar articles
-
A PCR based method to determine the Kalow allele of the cholinesterase gene: the E1k allele frequency and its significance in the normal population.J Med Genet. 1994 Mar;31(3):248-50. doi: 10.1136/jmg.31.3.248. J Med Genet. 1994. PMID: 8014977 Free PMC article.
-
Recognition of two new phenotypes segregating the E1k allele for plasma cholinesterase.Hum Hered. 1988;38(4):233-9. doi: 10.1159/000153790. Hum Hered. 1988. PMID: 3169798
-
Succinylcholine neuromuscular blockade in subjects heterozygous for abnormal plasma cholinesterase.Anesthesiology. 1981 Sep;55(3):231-5. doi: 10.1097/00000542-198109000-00008. Anesthesiology. 1981. PMID: 6267958
-
Plasma cholinesterase: gene and variations.Anesth Analg. 1993 Aug;77(2):380-6. doi: 10.1213/00000539-199377020-00027. Anesth Analg. 1993. PMID: 8346840 Review.
-
The Pennsylvania State University College of Medicine 1990 Bernard B. Brodie Lecture. Pharmacogenetics: past and future.Life Sci. 1990;47(16):1385-97. doi: 10.1016/0024-3205(90)90517-u. Life Sci. 1990. PMID: 2250557 Review. No abstract available.
Cited by
-
DNA mutation associated with the human butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites.Am J Hum Genet. 1992 May;50(5):1086-103. Am J Hum Genet. 1992. PMID: 1570838 Free PMC article.
-
Frequency and enzyme activity of the butyrylcholinesterase K-variant in a Turkish population.Eur J Clin Pharmacol. 2004 Feb;59(12):875-7. doi: 10.1007/s00228-003-0716-x. Epub 2004 Jan 21. Eur J Clin Pharmacol. 2004. PMID: 14735258
-
Proposed nomenclature for human butyrylcholinesterase genetic variants identified by DNA sequencing.Cell Mol Neurobiol. 1991 Feb;11(1):79-89. doi: 10.1007/BF00712801. Cell Mol Neurobiol. 1991. PMID: 2013061 Free PMC article.
-
A PCR based method to determine the Kalow allele of the cholinesterase gene: the E1k allele frequency and its significance in the normal population.J Med Genet. 1994 Mar;31(3):248-50. doi: 10.1136/jmg.31.3.248. J Med Genet. 1994. PMID: 8014977 Free PMC article.
-
A new detection method for the K variant of butyrylcholinesterase based on PCR primer introduced restriction analysis (PCR-PIRA).J Med Genet. 1994 Jul;31(7):576-9. doi: 10.1136/jmg.31.7.576. J Med Genet. 1994. PMID: 7966197 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
