Real-world evidence on biologic use in paediatric asthma: there but not there yet?
- PMID: 40551792
- PMCID: PMC12183747
- DOI: 10.1183/23120541.00209-2025
Real-world evidence on biologic use in paediatric asthma: there but not there yet?
Abstract
Persistent unmet needs in children with severe asthma on biologics call for precision medicine to optimise treatment, address steroid toxicity, and ensure cost-effective, sustainable care through national registries and health technology assessments https://bit.ly/4deHEpq.
Copyright ©The authors 2025.
Conflict of interest statement
Conflict of interest: W. Chen serves as an Early Career Investigator Delegate for the AstraZeneca Global Respiratory Leadership Forum. However, AstraZeneca had no role in the writing, review, or approval of this editorial, and no financial support was provided for this work.
Similar articles
-
Severe Paediatric Asthma Collaborative in Europe: real-world data on children on biologics.ERJ Open Res. 2025 Jun 23;11(3):00709-2024. doi: 10.1183/23120541.00709-2024. eCollection 2025 May. ERJ Open Res. 2025. PMID: 40551791 Free PMC article.
-
Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta2 agonists for the treatment of chronic asthma in children under the age of 12 years.Health Technol Assess. 2008 May;12(20):1-174, iii-iv. doi: 10.3310/hta12200. Health Technol Assess. 2008. PMID: 18485272
-
Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature.Health Technol Assess. 2001;5(26):1-149. doi: 10.3310/hta5260. Health Technol Assess. 2001. PMID: 11701099
-
A systematic review to examine the impact of psycho-educational interventions on health outcomes and costs in adults and children with difficult asthma.Health Technol Assess. 2005 Jun;9(23):iii-iv, 1-167. doi: 10.3310/hta9230. Health Technol Assess. 2005. PMID: 15929858
-
Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta-analysis.Cochrane Database Syst Rev. 2017 Mar 10;3(3):CD012591. doi: 10.1002/14651858.CD012591. Cochrane Database Syst Rev. 2017. PMID: 28282491 Free PMC article.
References
-
- Global Initiative for Asthma . Global Strategy for Asthma Management and Prevention, 2024. Available from https://ginasthma.org
Publication types
LinkOut - more resources
Full Text Sources
Miscellaneous