Expert Opinion on Management Advancements in Sarcopenia: From Muscle Wasting to Recovery

Abstract

Sarcopenia, an age-related condition marked by the decline of skeletal muscle mass, strength, and function, often leads to loss of function, disability, and diminished quality of life (QoL) in the elderly population. Despite its growing prevalence, sarcopenia is frequently underdiagnosed and inadequately managed. Timely detection and appropriate interventions are crucial to slowing disease progression and minimizing associated risks. As standardized guidelines and individualized management plans are necessary to improve clinical outcomes, this consensus paper presents expert insights into advancements in sarcopenia management, including diagnostic criteria and therapeutic interventions, and the need for personalized screening tools for Indian demographics. Furthermore, experts emphasized the importance of a multimodal approach, integrating resistance exercise, nutritional optimization, and emerging pharmacological therapies for effective sarcopenia treatment. The role of anabolic agents such as nandrolone decanoate in muscle preservation is explored, alongside considerations for patient selection and safety. This paper underscores the importance of a patient-centered approach, which addresses both functional recovery and overall well-being of individuals at risk or diagnosed with sarcopenia.