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Editorial
. 2025 Jul;4(7):101921.
doi: 10.1016/j.jacadv.2025.101921. Epub 2025 Jun 18.

The Evidence Surrounding Type B Dissection in Marfan Syndrome: Miles to Go Before We Sleep

Nupoor Narula  1 , Jonathan W Weinsaft  1 , Richard B Devereux  1 , Leonard N Girardi  2 , Mary J Roman  3
Affiliations
Editorial

The Evidence Surrounding Type B Dissection in Marfan Syndrome: Miles to Go Before We Sleep

Nupoor Narula et al. JACC Adv. 2025 Jul.
No abstract available

Keywords: Marfan syndrome; type B aortic dissection.

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Conflict of interest statement

Funding support and author disclosures Research support was provided by grants from the Vital Funds Project and the Michael Wolk Heart Foundation. Dr Narula is partially supported as a Bruce B. Lerman Clinical Scholar. Drs Narula, Roman, and Weinsaft are partially supported by the National Institutes of Health award R01 HL170570. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

Figure 1
Figure 1
Predictors of Type B Dissection in Marfan Syndrome Predictors of type B dissection in Marfan syndrome may include clinical phenotype, aortic phenotype, and underlying genotype in the setting of longer lifespan.
See this image and copyright information in PMC

References

    1. Narula N., Devereux R.B., Arbustini E., et al. Risk of type B dissection in Marfan syndrome: the cornell aortic aneurysm registry. J Am Coll Cardiol. 2023 doi: 10.1016/j.jacc.2023.08.055. - DOI - PubMed
    1. Murdoch J.L., Walker B.A., Halpern B.L., et al. Life expectancy and causes of death in the Marfan syndrome. N Engl J Med. 1972;286(15):804–808. doi: 10.1056/NEJM197204132861502. - DOI - PubMed
    1. Palumbo M.C., Redaelli A., Wingo M., et al. Impact of ascending aortic prosthetic grafts on early postoperative descending aortic biomechanics on cardiac magnetic resonance imaging. Eur J Cardiothorac Surg. 2022;61(4):860–868. doi: 10.1093/ejcts/ezab501. - DOI - PMC - PubMed
    1. Narula N., Schwartz Y., Devereux R.B., et al. Clinical and phenotypic correlates of mitral valve prolapse in Marfan syndrome: the Cornell Aortic Aneurysm Registry. J Am Heart Assoc. 2025;14(10):e040947. doi: 10.1161/JAHA.125.040947. - DOI - PMC - PubMed
    1. Narula N., Devereux R.B., Malonga G.P., et al. Pregnancy-related aortic complications in women with Marfan syndrome. J Am Coll Cardiol. 2021;78(9):870–879. doi: 10.1016/j.jacc.2021.06.034. - DOI - PubMed

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