Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun;40(6):e70233.
doi: 10.1002/bio.70233.

"Signal-Switching" Fluorescence Sensing of Fe3+ and Ascorbic Acid by Songaria Cynomorium Polysaccharide-Doped Carbon Dots of the Tibetan Medicinal Herb

Huan Wang  1   2   3 , Tianfeng Ma  1   2   3 , Wencheng Mu  1   2   3 , Cailin Wang  1   2   3 , Siqi Sheng  1   2   3 , Yanyan Jia  4 , Yongchang Lu  1   2
Affiliations

"Signal-Switching" Fluorescence Sensing of Fe3+ and Ascorbic Acid by Songaria Cynomorium Polysaccharide-Doped Carbon Dots of the Tibetan Medicinal Herb

Huan Wang et al. Luminescence. 2025 Jun.

Abstract

The Songaria Cynomorium polysaccharide-doped carbon dots (SP-CDs) were synthesized by carbonization-heating method. Songaria Cynomorium polysaccharide (PS) was the carbon source. Ethylenediamine (EDA), phosphoric acid (H3PO4), and concentrated hydrochloric acid (HCl) were dopants, respectively. The SP-CDs exhibited the maximum fluorescence emission wavelength of 540 nm under the excitation wavelength of 485 nm ("ON" state). After the introduction of Fe3+ with an intermediate bridging effect, the fluorescence intensity of SP-CDs was quenched due to the formation of the complex (SP-CDs/Fe3+) between SP-CDs and Fe3+ ("OFF" state). Subsequently, the fluorescence signal returned to "ON" due to the redox reaction between AA and Fe3+ when ascorbic acid was introduced into SP-CDs/Fe3+ solution. Therefore, the synthesized SP-CDs could be used as a "switch type" fluorescence sensor for detecting Fe3+ and AA. The analysis revealed that the linear range of Fe3+ extended from 0.05 to 500.00 μM, with the limit of detection (LOD) of 0.02 μM (S/N = 3). The scope of analysis for AA was determined to be within the range of 0.65-400.00 μM, with the limit of detection (LOD) of 0.09 μM (S/N = 3). Furthermore, the recommended fluorescence sensor was successfully employed for quantitatively detecting Fe3+ and AA in serum samples.

Keywords: AA; Fe3 +; ON–OFF–ON; SP‐CDs; fluorescence.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. T. Lv, J. Chen, Z. He, W. Chen, Y. Zong, and R. Du, “Studies of the Immunomodulatory Activity of Polysaccharides From the Stem of Cynomorium Songaricum Based on Intestinal Microbial Analysis,” Molecules 29 (2023): 143.
    1. P. B. S. Albuquerque, W. F. de Oliveira, P. M. dos Santos Silva, M. T. dos Santos Correia, J. F. Kennedy, and L. C. B. B. Coelho, “Skincare Application of Medicinal Plant Polysaccharides—A Review,” Carbohydrate Polymers 277 (2022): 118824, https://doi.org/10.1016/j.carbpol.2021.118824.
    1. Y. Liu, S. Lv, J. Gao, et al., “Study on the Stability and Cellular Affinity of Gelatin‐Polysaccharide Composite Films,” Journal of Biomedical Materials Research. Part A 108 (2020): 2230–2239.
    1. X. Niu, Y. Yao, Y. Li, C. Li, X. Pan, and L. Han, “The Role of the Ferroptosis Pathway in the Regulation of Polysaccharides for Human Health: A Review,” International Journal of Biological Macromolecules 231 (2023): 123349, https://doi.org/10.1016/j.ijbiomac.2023.123349.
    1. R. Zhang, L. Wang, F. Ettoumi, et al., “Ultrasonic‐Assisted Green Extraction of Peach Gum Polysaccharide for Blue‐Emitting Carbon Dots Synthesis,” Sustainable Chemistry and Pharmacy 24 (2021): 100555.

LinkOut - more resources