Declaration of competing interest AMD reports lecture honoraria from AstraZeneca, GSK and Sanofi, travel support from OrPha Swiss, MSD and Janssen, and advisory board participation with Gebro Pharma, Janssen and MSD, outside submitted work. DS reports the position of GOLD representative for Switzerland, an unrestricted grant from Curetis payed to the institution, lecture honoraria from AstraZeneca, Berlin-Chemie/Menarini, Boehringer Ingelheim, Chiesi, CSL Behring, Curetis AG, GSK, Merck, MSD, Novartis, Sanofi, Vifor, and Roche, and data safety monitoring / advisory board participation with AstraZeneca, Berlin-Chemie/Menarini, Boehringer Ingelheim, Chiesi, CSL Behring, Curetis AG, GSK, Merck, MSD, Roche, Novartis, Sanofi and Vifor, outside submitted work.