Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun 25:153:e73.
doi: 10.1017/S0950268825100137.

Prevalence of Mollicutes in pregnant women undergoing high-risk prenatal care at a maternal and child reference unit in Bahia, Brazil

Fabrícia Almeida Fernandes Santana  1 , Jéssica Bomfim  2 , Mariana Ferraz  2 , Victória Cardoso  2 , Jassy Borges  2 , Danielle Souto de Medeiros  2 , Maurício Grijó  2 , Guilherme B Campos  2 , Lucas Miranda Marques  1   2
Affiliations

Prevalence of Mollicutes in pregnant women undergoing high-risk prenatal care at a maternal and child reference unit in Bahia, Brazil

Fabrícia Almeida Fernandes Santana et al. Epidemiol Infect. .

Abstract

During pregnancy, colonization by genital mycoplasmas may be associated with adverse outcomes. This study was conducted to investigate the prevalence of four species of Mollicutes (Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma parvum, and Ureaplasma urealyticum) in pregnant women receiving high-risk prenatal care and to evaluate possible associated factors. Data collection included the application of a questionnaire and the collection of cervical swabs from pregnant women. Species identification was performed by real-time PCR. The overall prevalence of Mollicutes was 60.97%. 55.9% of pregnant women were colonized by Ureaplasma spp., and 19.51% by Mycoplasma spp. The prevalence rates by species were 48.78% for U. parvum, 11.59% for U. urealyticum, 18.9% for M. hominis, and 1.22% for M. genitalium. Age, 12 years of schooling or more, age at first sexual intercourse up to 14 years, third trimester of pregnancy, having undergone infertility treatment, presence of STI, and groin lymph nodes were associated with a higher prevalence of microorganisms. The results presented are of utmost importance for understanding the prevalence of these microorganisms, the characteristics of colonized pregnant women, and planning screening strategies and interventions that minimize the negative impacts of these infections.

Keywords: Mollicutes; abortion; high risk prenatal; mycoplasmas; pregnancy; ureaplasma.

PubMed Disclaimer

Conflict of interest statement

The authors declare none.

Figures

Figure 1.
Figure 1.
Coinfection between Mollicutes species in pregnant women receiving high-risk prenatal care in southwesternBahia (n = 100). Brazil, 2021-2022.
See this image and copyright information in PMC

References

    1. Stavart L, Baud D and Eyer M (2023) Ureaplasma urealyticum, Ureaplasma parvum et Mycoplasma hominis: Commensaux ou pathogènes? [Ureaplasma urealyticum, Ureaplasma parvum, and Mycoplasma hominis: commensals or pathogens?]. Revue Médicale Suisse. 19, 1835–1839. French. 10.53738/REVMED.2023.19.845.1835. - DOI - PubMed
    1. Murtha AP and Edwards JM (2014) The role of Mycoplasma and Ureaplasma in adverse pregnancy outcomes. Obstetrics and Gynecology Clinics of North America 41, 615–627. 10.1016/j.ogc.2014.08.010. - DOI - PubMed
    1. Stol K, et al. (2021) Perinatal infections with Ureaplasma. The Pediatric Infectious Disease Journal 40, S26–S30. 10.1097/INF.0000000000002859. - DOI - PubMed
    1. Redelinghuys MJ, et al. (2014) Antimicrobial susceptibility patterns of Ureaplasma species and Mycoplasma hominis in pregnant women. BMC Infectious Disease 14, 171. 10.1186/1471-2334-14-171. - DOI - PMC - PubMed
    1. Donders GGG, et al. (2017) Mycoplasma/Ureaplasma infection in pregnancy: To screen or not to screen. Journal of Perinatal Medicine 45, 505–515. 10.1515/jpm-2016-0111. - DOI - PubMed

MeSH terms