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Case Reports
. 2025 May 15:19:1908.
doi: 10.3332/ecancer.2025.1908. eCollection 2025.

Rare presentation of multicentric sebaceous carcinoma of the breast in a 33-year-old woman: diagnostic challenges and treatment approach

Izaberen Sampaio Estevam  1   2 , Mariana Macambira Noronha  1   3 , Júlia Matos Dubanhevitz  1   4 , Eric Lima Freitas Mota  1   5 , Ígor Giordan Duarte Jorge  1   6 , Conceição Aparecida Dornelas  1   7 , Diane Isabelle Magno Cavalcante  1   8 , Georgia Fiuza Alencar Araripe  9 , Márcio Marcondes Vieira  10
Affiliations
Case Reports

Rare presentation of multicentric sebaceous carcinoma of the breast in a 33-year-old woman: diagnostic challenges and treatment approach

Izaberen Sampaio Estevam et al. Ecancermedicalscience. .

Abstract

Sebaceous carcinoma of the breast (SCB) is an unusual neoplasm. To the best of our knowledge, only 30 cases have been reported in the literature. Due to its rarity, there is limited knowledge on how to manage patients with SCB. This article aims to describe a case of multicentric sebaceous breast carcinoma in a 33-year-old woman detailing the diagnostic process, historical findings and the treatment approach.

Keywords: adenocarcinoma sebaceous; case reports; triple negative breast neoplasms.

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Conflict of interest statement

All authors report no relationships that could be construed as conflicts of interest. All authors take responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation. There was no source of funding.

Figures

Figure 1.
Figure 1.. Breast specimen of the tumour demonstrating a multicentric manifestation.
Figure 2.
Figure 2.. Histologic section of the tumour in the breast, demonstrating a sebaceous differentiation.
Figure 3.
Figure 3.. Histologic section of the lymph node metastasis, demonstrating a sebaceous differentiation.
See this image and copyright information in PMC

References

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