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. 2025 Aug;51(8):1514-1517.
doi: 10.1007/s00134-025-07987-x. Epub 2025 Jun 25.

Renal replacement therapy

Stéphane Gaudry  1   2   3 , Nattachai Srisawat  4 , Michael Joannidis  5
Affiliations

Renal replacement therapy

Stéphane Gaudry et al. Intensive Care Med. 2025 Aug.
No abstract available

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Conflict of interest statement

Declarations: Not applicable. Conflicts of interest: SG declares no competing interest regarding the submitted manuscript. NS has received honoraria or research support from Vantive Healthcare Corp, and Novartis outside the submitted work. MJ has received honoraria or research support from Baxter Healthcare Corp, AM-Pharma, CLS Behring, Fresenius, Takeda, and Novartis outside the submitted work.

Figures

Fig. 1
Fig. 1
Renal replacement therapy in ICU. RRT = renal replacement therapy, AKI = acute kidney injury, CRRT = continuous renal replacement therapy, IHD = intermittent hemodialysis, SLED = sustained low-efficiency dialysis, PIRRT = prolonged intermittent renal replacement therapy, Kt/V = ([K] = clearance, [t] = time, and [V] = volume).
See this image and copyright information in PMC

References

    1. Gaudry S, Hajage D, Schortgen F et al (2016) Initiation strategies for renal-replacement therapy in the intensive care unit. N Engl J Med 375:122–133. 10.1056/NEJMoa1603017 - PubMed
    1. Barbar SD, Clere-Jehl R, Bourredjem A et al (2018) Timing of renal-replacement therapy in patients with acute kidney injury and sepsis. N Engl J Med 379:1431–1442. 10.1056/NEJMoa1803213 - PubMed
    1. Bagshaw S, Wald R, Adhikari N et al (2020) Timing of initiation of renal-replacement therapy in acute kidney injury. N Engl J Med 383:240–251. 10.1056/NEJMoa2000741 - PubMed
    1. Gaudry S, Hajage D, Martin-Lefevre L et al (2021) Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial. Lancet Lond Engl 397:1293–1300. 10.1016/S0140-6736(21)00350-0 - PubMed
    1. Vinsonneau C, Camus C, Combes A et al (2006) Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet Lond Engl 368:379–385. 10.1016/S0140-6736(06)69111-3 - PubMed

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