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. 2025 Oct;9(10):2114-2120.
doi: 10.1038/s41562-025-02230-5. Epub 2025 Jun 25.

Capturing the complexity of human strategic decision-making with machine learning

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Capturing the complexity of human strategic decision-making with machine learning

Jian-Qiao Zhu et al. Nat Hum Behav. 2025 Oct.

Abstract

Strategic decision-making is a crucial component of human interaction. Here we conduct a large-scale study of strategic decision-making in the context of initial play in two-player matrix games, analysing over 90,000 human decisions across more than 2,400 procedurally generated games that span a much wider space than previous datasets. We show that a deep neural network trained on this dataset predicts human choices with greater accuracy than leading theories of strategic behaviour, revealing systematic variation unexplained by existing models. By modifying this network, we develop an interpretable behavioural model that uncovers key insights: individuals' abilities to respond optimally and reason about others' actions are highly context dependent, influenced by the complexity of the game matrices. Our findings illustrate the potential of machine learning as a tool for generating new theoretical insights into complex human behaviours.

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Conflict of interest statement

Competing interests: The authors declare no competing interests.

References

    1. McKelvey, R. D. & Palfrey, T. R. Quantal response equilibria for normal form games. Games Econ. Behav. 10, 6–38 (1995). - DOI
    1. Camerer, C. F. Behavioral Game Theory: Experiments in Strategic Interaction (Princeton University Press, 2011).
    1. Gächter, S. Behavioral game theory. In Blackwell Handbook of Judgment and Decision Making (eds Koehler D. J. & Harvey, N.) 485–503 (Blackwell Publishing Ltd., 2004).
    1. Weizsäcker, G. Ignoring the rationality of others: evidence from experimental normal-form games. Games Econ. Behav. 44, 145–171 (2003). - DOI
    1. McKelvey, R. D. & Palfrey, T. R. An experimental study of the centipede game. Econometrica 60, 803–836 (1992). - DOI

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