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Editorial
. 2025 Jun 6;12(6):736.
doi: 10.3390/children12060736.

The Role of Global Longitudinal Strain in Detecting Early Left Ventricular Dysfunction in Pediatric Bicuspid Aortic Valve Patients

Mohammed A Mashali  1   2 , Isabelle Deschênes  1 , Carl V Leier  3 , Nancy S Saad  1   4
Affiliations
Editorial

The Role of Global Longitudinal Strain in Detecting Early Left Ventricular Dysfunction in Pediatric Bicuspid Aortic Valve Patients

Mohammed A Mashali et al. Children (Basel). .

Abstract

Global longitudinal strain (GLS), assessed via speckle tracking echocardiography (STE), is increasingly recognized as a sensitive and early indicator of left ventricular (LV) dysfunction in pediatric patients with bicuspid aortic valve (BAV) [...].

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Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Făgărășan A., Ghiragosian-Rusu S.-E., Ghiragosian C., Gozar L., Suteu C., Toma D., Al-Akel F.C., Cucerea M. Speckle strain analysis of left ventricular dysfunction in paediatric patients with bicuspid aortic valve—A pilot study. Children. 2024;11:1514. doi: 10.3390/children11121514. - DOI - PMC - PubMed
    1. Kusner J.J., Brown J.Y., Gleason T.G., Edelman E.R. The natural history of bicuspid aortic valve disease. Struct. Heart. 2023;7:100119. doi: 10.1016/j.shj.2022.100119. - DOI - PMC - PubMed
    1. Jackson V., Petrini J., Caidahl K., Eriksson M.J., Liska J., Eriksson P., Franco-Cereceda A. Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: A study of 300 patients undergoing open-heart surgery. Eur. J. Cardiothorac. Surg. 2011;40:e118–e124. doi: 10.1016/j.ejcts.2011.04.014. - DOI - PubMed
    1. Mubarik A., Sharma S., Law M.A. “Bicuspid aortic valve (archived).” In Statpearls [Internet] StatPearls; Publishing; Treasure Island, FL, USA: 2023. - PubMed
    1. Michelena H.I., Desjardins V.A., Avierinos J.-F., Russo A., Nkomo V.T., Sundt T.M., Pellikka P.A., Tajik A.J., Enriquez-Sarano M. Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community. Circulation. 2008;117:2776–2784. doi: 10.1161/CIRCULATIONAHA.107.740878. - DOI - PMC - PubMed

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