Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 Jun 9;16(6):697.
doi: 10.3390/genes16060697.

Editorial on Genomic Mosaicism in Human Development and Diseases

Xincen Xi  1 , Xiaoxu Yang  1
Affiliations
Editorial

Editorial on Genomic Mosaicism in Human Development and Diseases

Xincen Xi et al. Genes (Basel). .

Abstract

The individual genome continuously accumulates genetic variations from a zygote [...].

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Bizzotto S., Walsh C.A. Genetic mosaicism in the human brain: From lineage tracing to neuropsychiatric disorders. Nat. Rev. Neurosci. 2022;23:275–286. doi: 10.1038/s41583-022-00572-x. - DOI - PubMed
    1. Graham J.H., Schlachetzki J.C.M., Yang X., Breuss M.W. Genomic Mosaicism of the Brain: Origin, Impact, and Utility. Neurosci. Bull. 2023;40:759–776. doi: 10.1007/s12264-023-01124-8. - DOI - PMC - PubMed
    1. Hall J.G. Review and hypotheses: Somatic mosaicism: Observations related to clinical genetics. Am. J. Hum. Genet. 1988;43:355–363. - PMC - PubMed
    1. Gottlieb B., Beitel L.K., Trifiro M.A. Somatic mosaicism and variable expressivity. Trends Genet. 2001;17:79–82. doi: 10.1016/S0168-9525(00)02178-8. - DOI - PubMed
    1. Yang X., Yang C., Zheng X., Xiong L., Tao Y., Wang M., Ye A.Y., Wu Q., Dou Y., Luo J., et al. MosaicBase: A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Disease-related and Healthy Human Individuals. Genom. Proteom. Bioinform. 2020;18:140–149. doi: 10.1016/j.gpb.2020.05.002. - DOI - PMC - PubMed

Publication types

LinkOut - more resources