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. 2025 May 29;15(6):874.
doi: 10.3390/life15060874.

Surgical Repair of Bile Duct Injuries Due to Cholecystectomy-An Experience from a Referral Center in Slovenia

Irena Plahuta  1   2 , Špela Turk  1 , Barbara Lovrenčič Petreski  1 , Tomislav Magdalenić  1 , Stojan Potrč  1   2 , Arpad Ivanecz  1   2
Affiliations

Surgical Repair of Bile Duct Injuries Due to Cholecystectomy-An Experience from a Referral Center in Slovenia

Irena Plahuta et al. Life (Basel). .

Abstract

Background: Bile duct injury (BDI) during (laparoscopic) cholecystectomy has an incidence of up to 1.5%. This retrospective study aimed to report the outcomes of surgical repair of BDI due to these procedures at a tertiary referral center.

Methods: A retrospective review of patients' records was conducted. The BDI's clinical presentations, Strasberg classification, surgical repairs, and outcomes were reported.

Results: From 2003 to 2024, 47 BDIs were identified. In total, 34.0% were recognized intraoperatively. The BDI types included Strasberg types B (2, 4.3%), C (5, 10.6%), D (11, 23.4%), E1 (4, 8.5%), E2 (12, 25.5%), E3 (5, 10.6%), E4 (3, 6.4%), and E5 (5, 10.6%). The T-tube group included 6 (12.8%) patients, the primary repair and T-tube group included 10 (21.3%) patients, and the Biliodigestive anastomosis group included 31 (65.9%) patients. The overall morbidity rate was 40.4%, the major morbidity rate was 21.3%, and the mortality rate was 4.3%. Grade A patency was achieved in 95.6% of patients. In the Biliodigestive anastomosis group, the actuarial 1-, 5- and 10-year grade A patency rates were 77.0%, 70.0%, and 70.0%, respectively.

Conclusion: The rate of BDI remains stable. The outcomes of repairs in terms of complications and patency rates are comparable to those in other reports.

Keywords: bile duct injury; biliodigestive anastomosis; cholecystectomy; morbidity; mortality; patency.

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Conflict of interest statement

The authors declare no conflicts of interest. The sponsor had no role in the design, execution, interpretation, or writing of this study.

Figures

Figure 1
Figure 1
A study flow chart. The search excluded bile duct resections for cysts, neoplasms, and choledocholithiasis; liver resections for liver tumors and abscess drainages; surgery for gallbladder or perihilar cholangiocarcinoma; and pancreaticoduodenectomies. ERCP: Endoscopic retrograde cholangiopancreatography.
Figure 2
Figure 2
Patency of repairs of bile duct injuries. BDA: Biliodigestive anastomosis. Blue: BDA group; Purple: T-tube group; Green: Primary repair and T-tube group.
Figure 3
Figure 3
Kaplan–Meier curves of actuarial primary patency dependent on time. BDA: Biliodigestive anastomosis.
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References

    1. Sparkman R.S. 100th Anniversary of the First Cholecystectomy: A Reprinting of the 50th Anniversary Article From the Archives of Surgery, July 1932. Arch. Surg. 1982;117:1525. doi: 10.1001/archsurg.1982.01380360001001. - DOI - PubMed
    1. Blum C.A., Adams D.B. Who did the first laparoscopic cholecystectomy? J. Minim. Access Surg. 2011;7:165–168. doi: 10.4103/0972-9941.83506. - DOI - PMC - PubMed
    1. de’Angelis N., Catena F., Memeo R., Coccolini F., Martínez-Pérez A., Romeo O.M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., et al. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy. World J. Emerg. Surg. 2021;16:30. doi: 10.1186/s13017-021-00369-w. - DOI - PMC - PubMed
    1. Way L.W., Stewart L., Gantert W., Liu K., Lee C.M., Whang K., Hunter J.G. Causes and prevention of laparoscopic bile duct injuries: Analysis of 252 cases from a human factors and cognitive psychology perspective. Ann. Surg. 2003;237:460–469. doi: 10.1097/01.SLA.0000060680.92690.E9. - DOI - PMC - PubMed
    1. Pekolj J. Introduction. In: Pekolj J., Ardiles V., Glinka J., editors. Fundamentals of Bile Duct Injuries: From Prevention to Multidisciplinary Management. Springer International Publishing; Cham, Switzerland: 2022. pp. 1–5.

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