Moringa oleifera Lam.: A Nutritional Powerhouse with Multifaceted Pharmacological and Functional Applications
- PMID: 40566534
- PMCID: PMC12194112
- DOI: 10.3390/life15060881
Moringa oleifera Lam.: A Nutritional Powerhouse with Multifaceted Pharmacological and Functional Applications
Abstract
Moringa oleifera, often referred to as the "miracle tree", has gained widespread recognition for its exceptional nutritional profile and broad pharmacological potential. This review provides a comprehensive synthesis of the plant's botanical characteristics, taxonomy, cultivation practices, and biochemical composition. Special emphasis is placed on its rich content of bioactive secondary metabolites-such as flavonoids, alkaloids, phenolic acids, saponins, isothiocyanates, and glucosinolates-which underlie its diverse therapeutic effects. The paper compiles and analyzes evidence from over 200 peer-reviewed studies, documenting antioxidant, anti-inflammatory, antimicrobial, antidiabetic, anticancer, hepatoprotective, neuroprotective, and anti-obesity effects, among others. For instance, leaf extracts have demonstrated potent antioxidant and antidiabetic effects in both animal models and clinical trials, while seed-derived isothiocyanates have shown significant antibacterial and anticancer activity. In addition, clinical and in vivo data support M. oleifera's role in fertility regulation, cardiovascular protection, and neurodegenerative disease mitigation. Beyond its medicinal applications, the review highlights its growing use in functional foods, dietary supplements, and cosmeceutical products, reflecting its commercial and industrial relevance. By consolidating findings across disciplines, this review underscores the multifaceted value of M. oleifera as a nutraceutical and therapeutic resource.
Keywords: Moringa oleifera; antioxidant activity; cosmeceuticals; functional foods; nutrients; pharmacological properties; phytochemistry; traditional medicine.
Conflict of interest statement
The authors declare no conflict of interest.
Figures











Similar articles
-
Exploring the therapeutic role of Moringa oleifera in neurodegeneration: antioxidant, anti-inflammatory, and neuroprotective mechanisms.Inflammopharmacology. 2025 Jul;33(7):3653-3669. doi: 10.1007/s10787-025-01794-y. Epub 2025 May 31. Inflammopharmacology. 2025. PMID: 40448817 Review.
-
A comprehensive review of the phytochemicals, health benefits, pharmacological safety and medicinal prospects of Moringaoleifera.Heliyon. 2024 Mar 8;10(6):e27807. doi: 10.1016/j.heliyon.2024.e27807. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38496871 Free PMC article. Review.
-
Traditional processing, uses, phytochemistry, pharmacology and toxicology of Aconitum sinomontanum Nakai: A comprehensive review.J Ethnopharmacol. 2022 Jul 15;293:115317. doi: 10.1016/j.jep.2022.115317. Epub 2022 Apr 22. J Ethnopharmacol. 2022. PMID: 35469829
-
Nutritional content and renoprotective potential of miracle tree (Moringa oleifera).BioTechnologia (Pozn). 2025 Jun 30;106(2):223-239. doi: 10.5114/bta/204529. eCollection 2025. BioTechnologia (Pozn). 2025. PMID: 40703714 Free PMC article. Review.
-
Moringa oleifera regulates the health of people living with HIV in developing countries: a systematic review.Afr J AIDS Res. 2023 Nov;22(3):247-252. doi: 10.2989/16085906.2023.2277894. Epub 2023 Nov 28. Afr J AIDS Res. 2023. PMID: 38015892
References
-
- Fuglie L.J. Producing Food Without Pesticides: Local Solutions to Crop Pest Control in West Africa. Church World Service; Dakar, Senegal: 1998. pp. 1–158.
-
- Pareek A., Pant M., Gupta M.M., Kashania P., Ratan Y., Jain V., Pareek A., Chuturgoon A.A. Moringa oleifera: An Updated Comprehensive Review of Its Pharmacological Activities, Ethnomedicinal, Phytopharmaceutical Formulation, Clinical, Phytochemical, and Toxicological Aspects. Int. J. Mol. Sci. 2023;24:2098. doi: 10.3390/ijms24032098. - DOI - PMC - PubMed
-
- Gharsallah K., Rezig L., Rajoka M.S.R., Mehwish H.M., Ali M.A., Chew S.C. Moringa oleifera: Processing, Phytochemical Composition, and Industrial Applications. S. Afr. J. Bot. 2023;160:180–193. doi: 10.1016/j.sajb.2023.07.008. - DOI
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources