Validation of a deep learning model for computed tomography-derived fractional flow reserve

Vincent Pham^{1

2

3

4}, Fabien Picard^{2

3

4}, Sebastien Monnot⁵, Pierre Garrigoux⁶, Arnaud Jegou¹, Grégoire Dambrin¹, Jean-François Paul^{5

7}

Affiliations

¹ Department of Interventional Cardiology, Hôpital Privé Parly 2, Le Chesnay.
² Department of Cardiology, Cochin Hospital, Hôpitaux Universitaire Paris Centre, Assistance Publique des Hôpitaux de Paris.
³ INSERM U970, Paris Cardiovascular Research Center (PARCC), European Georges Pompidou Hospital.
⁴ Université Paris Cité.
⁵ Spimed-AI, Paris.
⁶ Department of Radiology, Hôpital Privé Parly 2, Le Chesnay.
⁷ Department of Radiology, Cardiac Imaging, Institut Mutualiste Montsouris, Paris, France.

Vincent Pham et al. Coron Artery Dis. 2025.

. 2025 Aug 1;36(5):434-436.

doi: 10.1097/MCA.0000000000001508. Epub 2025 Jun 25.

Vincent Pham^{1

2

3

4}, Fabien Picard^{2

3

4}, Sebastien Monnot⁵, Pierre Garrigoux⁶, Arnaud Jegou¹, Grégoire Dambrin¹, Jean-François Paul^{5

7}

¹ Department of Interventional Cardiology, Hôpital Privé Parly 2, Le Chesnay.
² Department of Cardiology, Cochin Hospital, Hôpitaux Universitaire Paris Centre, Assistance Publique des Hôpitaux de Paris.
³ INSERM U970, Paris Cardiovascular Research Center (PARCC), European Georges Pompidou Hospital.
⁴ Université Paris Cité.
⁵ Spimed-AI, Paris.
⁶ Department of Radiology, Hôpital Privé Parly 2, Le Chesnay.
⁷ Department of Radiology, Cardiac Imaging, Institut Mutualiste Montsouris, Paris, France.

No abstract available

References

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1. Paul J-F, Rohnean A, Giroussens H, Pressat-Laffouilhere T, Wong T. Evaluation of a deep learning model on coronary CT angiography for automatic stenosis detection. Diagn Interv Imaging 2022; 103:316–323.
1. Brendel JM, Walterspiel J, Hagen F, Kübler J, Paul J-F, Nikolaou K, et al. Coronary artery disease evaluation during transcatheter aortic valve replacement work-up using photon-counting CT and artificial intelligence. Diagn Interv Imaging 2024; 105:273–280.
1. Yang J, Shan D, Wang X, Sun X, Shao M, Wang K, et al. On-site computed tomography-derived fractional flow reserve to guide management of patients with stable coronary artery disease: the TARGET randomized trial. Circulation 2023; 147:1369–1381.