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Comment
. 2025 Jun 26;388(6754):1371-1372.
doi: 10.1126/science.ady9507. Epub 2025 Jun 26.

A caged drug enables precision delivery

Yuhao Xie  1 , Zhe-Sheng Chen  1
Affiliations
Comment

A caged drug enables precision delivery

Yuhao Xie et al. Science. .

Abstract

"GlycoCaging" uses gut bacteria to activate drugs for inflammatory bowel disease.

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  • Bespoke plant glycoconjugates for gut microbiota-mediated drug targeting.
    Ma WJ, Wang C, Kothandapani J, Luzentales-Simpson M, Menzies SC, Bescucci DM, Lange ME, Fraser ASC, Gusse JF, House KE, Moote PE, Xing X, Grondin JM, Hui BW, Clarke ST, Shelton TG, Haskey N, Gibson DL, Martens EC, Abbott DW, Inglis GD, Sly LM, Brumer H. Ma WJ, et al. Science. 2025 Jun 26;388(6754):1410-1416. doi: 10.1126/science.adk7633. Epub 2025 May 1. Science. 2025. PMID: 40310938

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