Nemolizumab Treatment Normalizes Dysregulated Microbiome in Lesional Prurigo Nodularis

Affiliations

¹ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
² Galderma, Lausanne, Switzerland.
³ Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
⁴ Department of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
⁵ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA; Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: alextsoi@umich.edu.

Free article

Ruiwen Zhou et al. J Invest Dermatol. 2025.

Free article

. 2025 Jun 25:S0022-202X(25)02231-6.

doi: 10.1016/j.jid.2025.06.1575. Online ahead of print.

¹ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
² Galderma, Lausanne, Switzerland.
³ Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
⁴ Department of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
⁵ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA; Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: alextsoi@umich.edu.

No abstract available

Keywords: 16S ribosomal RNA; Machine learning; Microbiome; Nemolizumab; Pruigo nodularis.

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